Journals
2018 EN
Glootz Kim · Kratzert Daniel · Himmel Daniel
+4 more
The univalent salt Ga(PhF) 2 + [Al(OR F ) 4 ] − (R F =OC(CF 3 ) 3 ) forms the strongly metal–metal bonded cluster tetracations [Ga II 2 (L) 4 ] 4+ and [Ga I 4 (L′) 8 ] 4+ , when it reacts with innocent ligands like phenanthroline (L=phen) or t ‐butylisonitrile (L′= t Bu‐NC). Their structures and energetics are discussed as a function of the employed ligands, supported by DFT calculations and Born–Fajans–Haber cycles.
Journals
2018 EN
Glootz Kim · Kratzert Daniel · Himmel Daniel
+4 more
The univalent salt Ga(PhF) 2 + [Al(OR F ) 4 ] − (R F =OC(CF 3 ) 3 ) forms the strongly metal–metal bonded cluster tetracations [Ga II 2 (L) 4 ] 4+ and [Ga I 4 (L′) 8 ] 4+ , when it reacts with innocent ligands like phenanthroline (L=phen) or t ‐butylisonitrile (L′= t Bu‐NC). Their structures and energetics are discussed as a function of the employed ligands, supported by DFT calculations and Born–Fajans–Haber cycles.
Journals
2018 EN
Fereidoonnezhad Masood · Shahsavari Hamid R. · Lotfi Elaheh
+5 more
The reaction of [(Me 2 S)AuCl] with an equimolar amount of benzyl isocyanide (PhCH 2 NC) ligand led to the formation of complex [(PhCH 2 NC)AuCl] ( 1 ). The solid‐state structure of 1 was determined using the X‐ray diffraction method. Through a salt metathesis reaction, the chloride ligand in 1 was replaced by pyrimidine‐2‐thiolate (SpyN − ) to afford the complex [(PhCH 2 NC)Au(η 1 ‐S‐Spy)] ( 2 ), which was characterized spectroscopically. The cytotoxic activities of 1 and 2 were evaluated against three human cancer cell lines: ovarian carcinoma (SKOV3), lung carcinoma (A549) and breast carcinoma (MCF‐7). Complex 2 showed higher cytotoxicity than cisplatin against SKOV3 and MCF‐7 cancer cell lines. It showed a strong anti‐proliferative activity with IC 50 of 7.80, 6.26 and 6.14 μM, compared with that measured for cisplatin which was 7.62, 12.36 and 11.47 μM, against A549, SKOV3 and MCF‐7 cell lines, respectively. The induction of cellular apoptosis by 2 was also studied on MCF‐7 cell line. Our results indicated that 2 could induce apoptosis in cancerous cells in a dose‐dependent manner.
Resource
2018 EN
Fereidoonnezhad Masood · Shahsavari Hamid R. · Lotfi Elaheh
+5 more
The cover image, by Masood Fereidoonnezhad et al., is based on the Full Paper ( Benzyl isocyanide)gold(I) pyrimidine‐2‐thiolate complex: Synthesis and biological activity , DOI: 10.1002/aoc.4200 . Design Credit: Eric Pipkin.
Journals
2018 EN
Hajipour Abdol R. · Abolfathi Parisa · TavangarRizi Zeinab
An interesting silica‐supported iron catalyst was successfully prepared and demonstrated as an efficient heterogeneous catalyst for cross‐coupling reactions of aryl halides. The as‐prepared nanocatalyst was well characterized and found to be highly efficient in Heck reaction under mild and sustainable conditions (water as solvent at 80 °C in short reaction time). Furthermore, the obtained catalyst was used as an efficient, inexpensive and green heterogeneous catalyst for Sonogashira cross‐coupling reactions of various aryl iodides and provided the corresponding products with moderate to good yields. This phosphine, copper and palladium‐free catalyst was simply recovered from the reaction mixture and recycled five times without substantial decrease in its catalytic activity.
Journals
2018 EN
GhorbaniChoghamarani Arash · Seydyosefi Zeinab · Tahmasbi Bahman
Boehmite nanoparticles were prepared by a simple and inexpensive procedure in water using commercially available materials without inert atmosphere. Then, the surface of the boehmite nanoparticles was modified using 3‐mercaptopropyltrimethoxysilane and subsequently zirconium oxide was supported on the modified surface. Zirconium oxide supported on boehmite nanoparticles (Pr.S‐ZrO@boehmite) was characterized using scanning electron microscopy, Fourier transform infrared spectroscopy, thermogravimetric analysis and inductively coupled plasma technique. The catalytic application of Pr.S‐ZrO@boehmite was studied in C–O and C–S coupling reactions for synthesis of valuable compounds such as ether and sulfide derivatives. All products were obtained in good to excellent yields and the catalyst could be recovered and reused several times without significant loss of catalytic efficiency. Furthermore, zirconium oxide is rarely used as catalyst for cross‐coupling reactions.
Journals
2018 EN
Vetr Fahime · MoradiShoeili Zeinab · Özkar Saim
Metal ferrites nanocrystallites, MFe 2 O 4 (M = Mn, Co, Ni, Zn) were prepared by coprecipitation method and characterized by a combination of physico‐chemical and spectroscopic techniques. MFe 2 O 4 nanoparticles having particle size in the range 10–35 nm were tested as catalysts in the oxidation of o‐phenylenediamine (OPD) to 2,3–diaminophenazine (DAP) using hydrogen peroxide as oxidant at room temperature. Kinetic data was collected for the catalytic oxidation of OPD to DAP by monitoring the UV–vis absorbance at 415 nm and fit well to the Michaelis–Menten model yielding kinetic parameters K m (Michaelis–Menten constant) and V max (maximum rate of reaction). MnFe 2 O 4 nanoparticles provide the highest catalytic activity in the oxidation of OPD to DAP at room temperature. A colorimetric method was developed based on the MnFe 2 O 4 /OPD system for the detection of H 2 O 2 in reaction solution. The method has a detection limit of 30 μM for H 2 O 2 and wide linear range.
Journals
2018 EN
Abbasi Zeinab · Salehi Mehdi · Khaleghian Ali
+1 more
Three new mononuclear Schiff base complexes [Co(L 1 ) 3 ( 1 ), VO(L 1 ) 2 ( 2 ) and Cu(L 2 ) 2 ( 3 )] were synthesized, characterized and used as a precursor for preparation of metal oxide nanoparticles. The crystal structure of compounds was determined using single crystal X‐ray diffraction. The Co(III) coordination sphere consists of three phenolato oxygens and three imino nitrogen atoms from three Schiff base ligands, thus forming a distorted octahedral geometry. In complex ( 2 ), the vanadium(IV) is five‐coordinated in a regular tetragonal pyramid fashion and the Cu(II) ion is four coordinated with a square‐planar geometry in the complex ( 3 ). The nanoparticles were characterized by Fourier transform infrared spectroscopy (FT‐IR), X‐ray powder diffraction (XRD) and field emission scanning electron microscopy (FE‐SEM). In vitro cell proliferation via MTT assay was studied to calculate the cytotoxicity of complexes and metal oxide nanoparticles against gastric cancer cell line (MKN‐45). The results showed that all compounds have anticancer activity with dose–response dependency.
Journals
2018 EN
Hamooleh Zeinab · Salimi Beni Alireza · Shakerzadeh Ehsan
The adsorption of oxazole and isoxazole molecules over the pristine B 12 N 12 nanocluster is investigated in terms of its geometric, the adsorption energies and the electronic properties using density functional theory calculations. The results indicate that the pristine cluster effectively chemisorbs with the oxazole and isoxazole molecules through their nitrogen atoms; whereas the interaction through the oxygen atoms is not considerable. The HOMO‐LUMO gap of the cluster decrease by the adsorption of heterocycle rings. The role of solvent in improving the adsorption properties over the B 12 N 12 surface is also considered. The obtained adsorption energies in aqueous medium are more negative than gas phase implied to the stability of the B 12 N 12 / heterocycles complexes in the aqueous medium. Indeed, the interactions of some oxazole and isoxazole derivatives with this cluster are also investigated. The current study provides the knowledge about the performance of the B 12 N 12 cluster in adsorbing oxazole and isoxazole moleculest.
Journals
2018 EN
Saberi Zeinab · Rezaei Behzad · Khayamian Taghi
A new fluorimetric aptasensor was designed for the determination of adenosine triphosphate (ATP) based on magnetic nanoparticles (MNPs) and carbon dots (CDs). In this analytical strategy, an ATP aptamer was conjugated on MNPs and a complementary strand of the aptamer (CS) was labeled with CDs. The aptamer and its CS were hybridized to form a double helical structure. The hybridized aptamers could be used for the specific recognition of ATP in a biological complex matrix using a strong magnetic field to remove the interfering effect. In the absence of ATP, no CDs–CS could be released into the solution and this resulted in a weak fluorescence signal. In the presence of ATP, the target binds to its aptamer and causes the dissociation of the double helical structure and liberation of the CS, such that a strong fluorescence signal was generated. The increased fluorescence signal was proportional to ATP concentration. The limit of detection was estimated to be 1.0 pmol L –1 with a dynamic range of 3.0 pmol L –1 to 5.0 nmol L –1 . The specific aptasensor was applied to detect ATP in human serum samples with satisfactory results. Moreover, molecular dynamic simulation (MDS) studies were used to analyze interactions of the ATP molecule with the aptamer.