Journals
2025 EN
Sahebjam Mohammad · Poorhosseini Hamidreza · Haji Ali Arezoo
+2 more
ABSTRACT Antiphospholipid syndrome (APS) is well known for its association with arterial and venous thrombosis. Intracardiac thrombosis—more often involving the right atrium—is a serious manifestation of the disease. We describe an APS case with a thrombosis in the right ventricular outflow tract (RVOT), which underwent regression after aggressive anticoagulation.
Journals
2025 EN
Altunbulak Halil İbrahim · Altunbulak Bilal · Altunbulak Ahmet Yasir
ABSTRACT Volvulus and torsion are life‐threatening emergencies requiring prompt diagnosis and surgical intervention. This study presents cases gallbladder torsion, lung torsion, mesenteroaxial gastric volvulus. Each case emphasizes the role of advanced imaging, particularly computed tomography (CT), in identifying these conditions. Despite timely surgical management, outcomes vary depending on the degree of ischemia and the patient's overall condition. Early recognition and intervention are crucial to prevent complications such as necrosis and multiorgan failure. Increased awareness and rapid surgical treatment can significantly improve patient outcomes.
Journals
2025 EN
Ngereja Shukrani John · Nhungo Charles John · Petro Ezekiel
+9 more
ABSTRACT Penile pyoderma gangrenosum is a rare but important differential diagnosis for ulcerative lesions of the genital region. Early recognition and systemic treatment, especially with corticosteroids, are crucial for effective management and avoiding the penile mutilating effect of the disease. Clinicians should consider PPG in cases of unexplained genital ulcers, particularly in the absence of infection or trauma.
Journals
2025 EN
Barghouth Ibrahim · Hassan Qussai · Saad Anas
+2 more
ABSTRACT Renal lymphangiectasia is a rare condition resulting from miscommunication between renal and retroperitoneal lymphatic ducts, causing ductal dilatation and lymphatic fluid collection. In this report, we present this condition and highlight an uncommon management approach involving cyst marsupialization. A 24‐year‐old female presented with flank pain and lumbar tenderness. Ultrasonography revealed a fluid collection, further evaluated by contrast‐enhanced CT, which provided additional details and ruled out urine as the source. Fluid analysis confirmed its lymphatic origin, leading to a diagnosis of renal lymphangiectasia. The condition was managed with marsupialization into the peritoneal cavity. At a one‐year follow‐up, the patient's symptoms had resolved, and ultrasonography showed that the kidney was decompressed with no fluid collection. This case of renal lymphangiectasia underscores its diagnostic challenges and sheds light on the rarely reported marsupialization technique, demonstrating its potential effectiveness and contributing to the growing literature on this rare condition.
Journals
2025 EN
Aldakak Mohammad Alaa · Ahmad Aows · Ahmad Raneem
+2 more
ABSTRACT Cystic echinococcosis (CE), caused by Echinococcus granulosus , is a zoonotic disease endemic in many pastoral regions. Pulmonary involvement, although less common than hepatic, may present with nonspecific respiratory symptoms and mimic other pathologies such as tuberculosis, posing a diagnostic challenge. We report a case of a 17‐year‐old Arab female from an endemic area who presented with cough, hemoptysis, fever, and general malaise. Chest imaging revealed a cavitary lesion in the upper lobe, raising suspicion of pulmonary tuberculosis or fungal infection. Laboratory findings showed leukocytosis and elevated inflammatory markers. Bronchoscopy and microbiological workup were negative for TB and fungi, though Klebsiella was cultured. Despite initial improvement with antibiotics, the definitive diagnosis was established intraoperatively after surgical resection revealed a complicated hydatid cyst. Postoperative culture identified Pseudomonas , and histopathology confirmed hydatid disease. This case highlights the diagnostic difficulty of pulmonary CE, particularly when imaging mimics tuberculosis. The upper lobe location and cavitary appearance contributed to initial misdirection. A lack of response to empirical therapy should prompt reconsideration of differential diagnoses, especially in endemic regions. Pulmonary hydatid cysts may present atypically and resemble more prevalent conditions like tuberculosis. Clinical vigilance, especially in endemic areas, is critical for timely diagnosis and appropriate management.
Journals
2025 EN
AlBadri Sajjad Ghanim · Duhan Aditya · AlTaie Rania H.
+2 more
ABSTRACT Jacobsen syndrome is a rare 11q deletion disorder with multisystem involvement. This case highlights a complex unbalanced 11;15 translocation, olfactory bulb agenesis, extensive white matter abnormalities, and severe endocrinopathies, emphasizing the need for comprehensive genetic and neuroimaging evaluations.
Journals
2025 EN
Abrar Sakib · Ahmed Shah Tanvir · Khalil Ibrahim
+1 more
ABSTRACT Myasthenia gravis (MG) is a chronic autoimmune neuromuscular disorder that leads to muscle weakness and rapid fatigue, often exacerbated by thymoma, a tumor of the thymus gland. This case report presents the clinical management of a 40‐year‐old female with MG complicated by thymoma, who presented with a severe myasthenic crisis. The patient required intensive care, including respiratory support, plasmapheresis, and immunosuppressive therapy. Initial evaluations confirmed the diagnosis of MG through the detection of high levels of anti‐acetylcholine receptor antibodies, and a CT scan revealed a thymic mass, indicative of thymoma. The management strategy included acetylcholinesterase inhibitors, immunosuppressive agents, and supportive therapies to stabilize the patient. The patient responded positively to plasmapheresis, which significantly improved her condition. Follow‐up CT imaging confirmed the presence of thymoma, reinforcing the need for further investigation into surgical interventions such as thymectomy. The report also emphasizes the critical role of a multidisciplinary approach in managing MG with thymoma, underscoring the importance of early diagnosis and timely intervention to prevent recurrent crises. Additionally, it discusses the evolving role of thymectomy in MG patients with thymoma and the potential of newer treatments, such as complement inhibitors, for refractory cases. This case highlights the complexities of managing MG complicated by thymoma and stresses the importance of ongoing research into therapeutic strategies. Early diagnosis, effective management, and continuous monitoring remain essential to optimizing outcomes for patients with these complex conditions.
Journals
2025 EN
Mansour Marah · Swaid Komait · Razouk Marah
+4 more
ABSTRACT Cervical leiomyomas are rare pelvic tumors, with interstitial subtypes being the least common. This case highlights a 44‐year‐old female with a 14‐mm interstitial cervical leiomyoma, successfully treated with myomectomy. This approach preserved fertility, demonstrating its feasibility as an alternative to hysterectomy for select patients.
Journals
2025 EN
AlBadri Sajjad Ghanim · Duhan Aditya · AlTaie Rania H.
+4 more
ABSTRACT Neurosarcoidosis with hypothalamic–pituitary involvement is rare and challenging to diagnose, requiring MRI and systemic clues for confirmation. High‐dose corticosteroids are essential but often necessitate steroid‐sparing agents due to side effects. Multidisciplinary care and vigilant follow‐up are critical for managing persistent symptoms and preventing complications.
Journals
2025 EN
Abutu Stephanie · ElDin Mohammad · Raju Prashanth
+1 more
ABSTRACT Significant implications, particularly in high‐risk settings such as driving. This case highlights the diagnostic challenges in identifying this condition, which necessitate a comprehensive evaluation to rule out structural or electrical cardiac abnormalities and confirm the diagnosis through careful monitoring. The proposed pathophysiology involves exaggerated vagal responses or inappropriate sympathetic withdrawal, although the exact mechanisms remain unclear. Management hinges on a tailored, trigger‐focused approach, emphasizing patient education and behavioral modifications to prevent a recurrence. Increased awareness of laughter‐induced syncope is vital for timely diagnosis, effective management, and the prevention of serious adverse outcomes.