ASSESSMENT OF GRAPE SEEDS AS A SOURCE OF ANTIOXIDANT COMPOUNDS

The grape seeds extracted with various organic solvents (methanol, ethanol, acetone and chloroform) either pure (100%) or mixed with 30, 50 and 50% water (except chloroform) were evaluated for its content of antioxidant compounds; i.e. phenolics and flavonoids (by HPLC technique) and/or antioxidant activities (by DPPH test). The extraction yield was ranged between 6-10% depending on solvent type and significantly increased by mixing with water with various percentages. Total phenolics, total flavonoids and antioxidant activity of grape seed extracts were affected by type of solvent. The highest total phenolic compounds and total flavonoids was recorded in methanol 70% extract, while the lowest one was in water 100% extract.

Effect of (Arthrospira platensis) Spirulina and (Nannochloropsis gaditana) Nannochloropsis supplementation on growth performance, feed utilization and carcass composition of Nile tilapia (Oreochromis niloticus)

The status of vitamin D in neonates with hypoxic ischemic encephalopathy

Vitamin D deficiency is a worldwide problem associated with wide spectrum of diseases, ranging from neurological disorders to chronic inflammatory conditions. Objectives: This is a cross sectional case control study performed to compare vitamin D serum levels between full term neonates with hypoxic ischemic encephalopathy (HIE) and normal healthy neonates and to determine if there is an association between serum vitamin D levels and neonatal hypoxic ischemic encephalopathy (HIE). Patients and methods: This study included 60 full term neonates; 30 of them had the criteria of moderate to severe HIE encephalopathy and the others is clinically free. We measured the serum levels of vitamin D using ELISA in both groups and the mothers of diseased neonates. Results: Neonates with hypoxic ischemic encephalopathy had a significant lower (25(OH) vitamin D) than controls (P-value ≤ 0.001), half of them (50%) had deficient levels of vitamin D, 23.3% had insufficient levels and 26.7 had normal levels of vitamin D. The control group had normal level in 90% and only 10% had insufficient levels of vitamin D and there were significant lower levels in serum maternal vitamin D below normal. Conclusion: Full-term neonates with HIE had lower serum levels of vitamin D than healthy neonates with positive correlations between neonatal serum vitamin D levels and their maternal levels.

ROLE OF NECK IMAGING REPORTING AND DATA SYSTEM (NIRADS) IN THE PREDICTION OF LOCAL AND REGIONAL RECURRENCE OF HEAD AND NECK SQUAMOUS CELL CARCINOMA BY CROSS SECTIONAL IMAGING MODALITIES

Background: Detection of residual, recurrent, or second primary malignancies in head and neck cancers treated patients can be challenging. Soft tissue changes and anatomical disfigurement seen after surgery, radiotherapy, and chemotherapy can distort the anatomy of the head and neck and make post treatment imaging reporting very complex. Aim of work: To evaluate the performance of the Neck imaging, and reporting data system template recently created by the American College of Radiology (ACR) Committee in the prediction of local and regional disease recurrence or persistence of head and neck squamous cell carcinoma after treatment by using CE MRI/ CT, and PET-CT in inconclusive cases. Patients and Methods: 116 scans for 55patients with head and neck squamous cell cancerswere included after finishing their treatment, reporting done using the ACR NI-RADS reporting template and lexicon and NI-RADS category was assigned to each scan, the accuracy of this categorization was done by correlation with our gold standard: tissue pathological examination and/ or three months interval follow up scan. Results: Out of the 116 scans included in our study, we had 232 targets for primary tumour sites and lymph nodes, the overall tumour recurrence have occurred in 53 targets out of the total of 232, with a total tumour recurrence rate of 22.8%, the recurrence rates for each NI-RADS category for the primary tumour site were: 3.9% (2/51) for NI-RADS 1 category, 17.6% (3/17) for NI-RADS 2a category, 18.2% (4/22) for NI-RADS 2b category , and 76.9% (20/26) for NI-RADS 3 category. Regarding the lymph nodes, the recurrence rates for the different NI-RADS categories were: 3.8% (3/80) for NI-RADS 1 category, 7.1% (1/14) for NI-RADS 2 category, and 81.8% (18/22) for NI-RADS 3 category. The recurrence rates for combined NI-RADS categories for both the primary tumour site and lymph nodes were (Table 7): 3.8% (5/131) for NI-RADS 1 category, 19.6% (10/51) for NI-RADS 2 category, and 76.2% (38/48) for NI-RADS 3 category. Conclusion: The performance of the ACR NI-RADS reporting system and its linked management recommendations is excellent, with statistically significant discrimination in between the different NIRADS categories for either the primary tumour site, lymph nodes and for both combined. The use of NI-RADS can help to direct the management plans towards more proper options. *Radiodiagnosis,** Clinical Oncology and Nuclear Medicine, Faculty of Medicine, Ain Shams University Corresponding : Manar Maamoun Ashour

EVALUATION OF SERUM PROCALCITONIN, SERUM IRON AND RE.D CELL DISTRIBUTION WIDTH (RDW) AS NOVEL BIOLOGICAL MARKERS IN INFLAMMATORY BOWEL DISEASES.

DETECTION OF AFLATOXINS IN UHT AND POWDERED FLAVORED MILK

EFFECT OF NISIN AS A BIOPRESERVATIVE ON SHELF LIFE OF PASTEURIZED MILK

RESPONSES OF THE RODLET CELLS TO METACERCARIAL INFECTIONS IN OREOCHROMIS NILOTICUS

La cortesía verbal: Análisis pragmático lingüístico de las estrategias de interpelación en Los ochenta son nuestros, de Ana Diosdado

El acto de habla del insulto y apelativos cariñosos en Los ochenta son nuestros, de Ana Diosdado