Diabetic disease and its chronic complications is a public health problem that affects millions of people all over the world. Feet diabetics need private care by using appropriate shoes and socks, to avoid friction, sweating and high temperature. Diabetic socks have to attain an effective thermal comfort and higher appraisal performance. To achieve these conditions, the diabetic socks have to attain comfortable fit, no pressure points or seams on fingers, suitable size, classified as spring-summer or autumn-winter and also to avoid high temperature. The specifications of the diabetic socks sold in the market consist of its material combination, size and chemical treatments. No definite physical mechanical properties of diabetic socks are proposed. Diabetic socks taken from the market, with appropriate price, were evaluated for both thermal and non-thermal properties. The tested samples demonstrate a great variability’s in the fabric construction and properties. By analyzing the tested socks, the proposed values concerning the properties of diabetic socks for summer and winter are introduced. Moreover, relative geometrical mean of thermal comfort properties was proposed for determining a global measure of diabetic sock properties.
Background Prolongation of the QTc interval may lead to life threatening arrhythmias. QTc prolongation is common in intensive care unit (ICU) patients. The objectives of this study were to identify the role of drug-drug interactions (DDIs) and other predictors (age, sex, cardiovascular diseases, and electrolyte abnormalities) in life threatening QTc prolongation in patients admitted to medical (M), surgical (S) and emergency (E) ICUs. Methods This prospective, observational study included patients above the age of 18 years who were admitted to SICU, EICU, and MICU at a tertiary respiratory referral center. Electrocardiogram (ECG) monitoring was performed during the first 5 days of ICU admission. Risk factors and DDIs which were anticipated to be associated with the prolongation of the QTc interval were assessed for all patients. Results Two hundred patients were included in the study. QTc prolongation occurred in 10.7% of patients and the majority of patients presenting with QTc prolongation had creatinine levels above 1.3 mg/dL during their 5 days of ICU admission. Incidence of pharmacodynamic (PD) DDIs was significantly higher in patients with QTc prolongation vs. other patients. Creatinine levels above 1.3 mg/dL and PD DDIs were associated with QTc prolongation during 5 days of ICU admission. Conclusions High serum creatinine and PD DDIs can increase the risk of QTc prolongation in patients admitted to the ICU. QTc interval measurements should be performed prior to initiation or after starting any drug that is associated with QT prolongation, specifically in patients with the known risk factors.
Different studies have reported contradictory results regarding the relationship between iron deficiency anemia (IDA) and febrile seizure (FS). The present study was conducted to determine the effect of IDA on FS in children.
Introduction: Alzheimer's disease (AD), which is a progressive neurodegenerative disorder, causes structural and functional brain disruption. MS4A6A, TREM2, and CD33 gene polymorphisms loci have been found to be associated with the pathobiology of late-onset AD (LOAD). In the present study, we tested the hypothesis of association of LOAD with rs983392, rs75932628, and rs3865444 polymorphisms in MS4A6A, TREM2, CD33 genes, respectively. Methods: In the present study, 113 LOAD patients and 100 healthy unrelated age- and gender-matched controls were selected. DNA was extracted from blood samples by the salting-out method and the genotyping was performed by RFLP-PCR. Electrophoresis was carried out on agarose gel. Sequencing was thereafter utilized for the confirmation of the results. Results: Only CD33 rs3865444 polymorphism revealed a significant difference in the genotypic frequencies of GG ( P = 0.001) and GT ( P = 0.001), and allelic frequencies of G ( P = 0.033) and T ( P = 0.03) between LOAD patients and controls. Conclusion: The evidence from the present study suggests that T allele of CD33 rs3865444 polymorphism is associated with LOAD in the studied Iranian population.
Background: Wastewater contaminated with dyes such as Reactive Blue 203 can produce a lot of health problems if it is released into the environment without a suitable treatment. Although there are several studies on dye removal from wastewater, removal of Reactive Blue 203 has not been investigated by hybrid methods. Therefore, the aim of this study was to investigate the removal of Reactive Blue 203 from aqueous solution, using combined processes of zinc oxide (ZnO) nanoparticles, Fe(VI) oxidation process, and UV radiation. Methods: The removal of dye from aqueous solution using ZnO nanoparticles, Fe(VI) oxidation process, and UV radiation was individually evaluated. Then, the results of combined methods were compared. Hydraulic retention time (HRT), pH, and temperature were the most important factors which were investigated in this study. Results: ZnO nanoparticles, Fe(VI) oxidation process, and UV radiation were able to remove 97%, 71%, and 47% of the dye in the optimal conditions, respectively. Also, the removal of dye using combination of Fe(VI) oxidation process/UV radiation, ZnO nanoparticles/Fe(VI) oxidation process, and ZnO nanoparticles/UV radiation under optimum conditions was 100%. It seems that the combined methods were significantly more effective than the methods alone for removal of dye from water. Conclusion: UV radiation alone is a simple and efficient method for removal of Reactive Blue 203 from water. Removal of Reactive Blue 203 using Fe(VI) oxidation process can be completed in a fraction of second, therefore, it can be categorized as a rapid reaction. Keywords: Wastewater, Ultraviolet rays, Zinc oxide, Adsorption
Background: Industrial dyes are toxic and carcinogenic, therefore, they should be removed from wastewater. The aim of this study was to investigate the removal of acid orange 7 Dye from wastewater using ultraviolet (UV) radiation, MgO nanoparticles, ultrasonic method alone and in combination with each other. Methods: The effects of some factors such as temperature, pH, hydraulic retention time (HRT), UV power, and concentration of MgO nanoparticles on the removal of Acid Orange 7 dye from synthetic wastewater using different methods were investigated. Also, adsorption isotherms for MgO nanoparticles and kinetics for UV radiation were investigated. Results: The optimum HRT was 55 minutes while the temperature was not effective in dye removal using the ultrasonic method. Under optimum conditions for UV irradiation method (HRT = 70 minutes, UV power = 170 mW/cm2, and temperature = 10 ̊C), 58% of the dye was removed. However, under optimum conditions for MgO nanoparticles method (HRT = 15 minutes, temperature = 20 ̊C, and ratio of MgO nanoparticles to the initial dye concentration = 67.2), 82% of the dye was removed. By combining these methods, the dye removal efficiency was significantly increased. The combination of ultrasonic method and MgO nanoparticles had no significant effect on increasing the dye removal efficiency from wastewater. It was revealed that dye removal using UV radiation can be described by the first-order kinetics. Conclusion: According to the results, UV radiation has a synergistic effect on the dye adsorption process by MgO nanoparticles. Therefore, the combination of these methods can be effective for the removal of dye from wastewater.
Background : Rheumatoid arthritis is a progressive autoimmune disease with variable clinical symptoms. This study aimed to investigate the effectiveness of cognitive behavioral training on C-reactive protein (CRP) and depression in patients with rheumatoid arthritis. Methods : This research was a semi-experimental study with a pretest-posttest design and a control group. The statistical population of this study involved all women suffering from rheumatoid arthritis who went to Iran Rheumatology Center. From among them, 60 individuals were randomly selected and consigned to the control and experimental groups. The control group received only medication, and an educational package about rheumatoid arthritis provided for them. Beck’s depression and biochemical evaluations questionnaires were used to measure dependent variables. To analyze the data, multivariate analysis of covariance and SPSS. 22 software were used. Results : The mean (SD) of depression in the experimental group in the pretest was 25.5 (3.8), which decreased to 18.9 (4.2) in the post-test (P < 0.01), but the mean (SD) of the control group was not statistically significant. Also, the mean (SD) of the CRP in the experimental group was 27.3 (6.9) in the pretest, which increased to 22.8 (4.6) in the post-test (P < 0.01), but the mean (SD) of the control group was not statistically significant. Conclusion : This research revealed that cognitive behavioral training led to a reduction of CRP and depression in patients with rheumatoid arthritis.