Hardaliyenin HT-29, DU-145, HeLa Kanser Hücreleri ve CF-1 (Fare Embriyonik Fibroblast) Hücresi FoxM1 Gen Expresyon Seviyelerine Etkisi
Elektropüskürtme Yönteminin Probiyotik Mikroorganizmaların Mikrokapsülasyonda Kullanımı
Fonksiyonel Dondurma
Pestisit Analizlerinde Asetilkolinesteraz İnhibisyonuna Dayalı İletken Polimer Esaslı Biyosensörler
Implementation of a “Self-Sufficient Ageing” Policy and Possible Challenges: Case of Turkey
The policies of socioeconomic protection of older adults in most parts of the world are being redesigned in the scope of value-added targets, such as active ageing, successful ageing, or creative ageing. The main purpose here is, of course, enabling older adults self-sufficient and beneficial both for themselves and their social environment, instead of being simply the passive beneficiaries of the public support mechanisms. Turkey has a population which is still young but ageing very rapidly and will reach to the same point as Europe today in a relatively much shorter time. However, the country still seems to be away from conducting systematic and holistic measures, except for a few ineffective strategy papers and legal regulations. Therefore, Turkey must immediately design a new policy agenda in conformity with its traditional and historical advantages. Revitalizing the intergenerational solidarity bonds, in this regard, may be the best cost-effective solution to complement formal measures in the provision of social protection and in the process of active ageing. However, this traditional protection net is under attack of increasingly transforming socioeconomic conditions. Consequently, as one of the most rapidly ageing countries in the world, Turkey should immediately stimulate studies and debates over a healthy, functional, and effective ageing period and caring issues. Otherwise, governments will be blindsided by the socioeconomic, psychological, cultural, and physiological problems related to the ageing process. In the light of these facts, the main purpose of this study is to discuss policy recommendations to create a self-sufficient ageing period for older adults in the context of Turkish case.
Yenice–Davutköy (Çanakkale) Sulama Göletlerinin Fizikokimyasal ve Mikrobiyolojik Kalitesinin Araştırılması
The aim of this study is to determine seasonally water quality characteristics irrigation ponds. Surface water samples were collected from three different sampling points in Yenice and Davutköy irrigation ponds (NW Turkey) for four different seasons. The parameters of dissolved oxygen, pH, salinity, electrical conductivity, chemical oxygen demand, biochemical oxygen demand, ammonium, nitrite, nitrate, total hardness, chloride and sodium adsorption rate (SAR) were investigated for Yenice and Davutköy irrigation water quality. According the national and international water quality standards, physicochemical parameters were determined under permissible level. In addition, sampling ponds are located C1−S1 class of ABD salinity diagrams. This result means that salinity and sodium values of water are suitable for ecological system and can be using for irrigation. Furthermore, the microbial quality of irrigation water for the ponds were determined that rate of mesophyll and psychotropic bacteria are connected with temperature. It is detected that the term of low temperature is high level of psychotropic bacteria and the term of high temperature increase the number of mesophyll bacteria. Pearson correlation analysis between the results of the statistical psychotropic aerobic count and temperature significant was found a strong negative correlation (r= -0,635). Fecal pollution indicator as the number of E.coli stations in Davutköy pond in the summer sampling were determined 110 cfu/100ml and 50 cfu/100ml, respectively. E.coli was not detected other stations and sampling time. Finally, according to obtained analysis results are determined that water qualities for Yenice and Davutköy ponds are suitable for agriculture activities.
Türkiye‘deki Zeytinyağı İşletmelerinin Üretim Süreçleri ve Kapasite Kullanımları Açısından Değerlendirilmesi
Calismada, ulkemizde faaliyet gosteren zeytinyagi uretim tesislerinin mevcut durumunu ortaya koyabilmek icin veri toplama ve degerlendirme calismalari gerceklestirilmistir. Ulkemizde cogunlukla kucuk ve orta olcekli isletmelerden olusan ticari olarak faaliyet gosteren 1000 civarinda zeytinyagi isletmesi bulunmaktadir. Bu tesislerde, sezonda yaklasik 1 milyon ton yaglik zeytin islenmekle birlikte, isletmelerin toplam maksimum kapasitesi yaklasik 5 milyon ton yaglik zeytin olarak tahmin edilmektedir. Sektorun kapasite kullanim oraninin ortalamasi %20 civarindadir. Zeytinyagi uretim tesislerinin yaklasik %71’i uc fazli, %27’si iki fazli ve %2’si tas baski olarak faaliyet gostermektedir. Uc fazli olarak faaliyet gosteren isletmelerde kullanilan dekantorlerin, %78’i herhangi bir kapasite ve verim kaybi olmadan 2 faza donusturulebilirken, %2’si donusemez niteliktedir. Tesislerin yaklasik %89’u, olusan karasularini buharlastirma lagunlerinde depolamaktadir.
Expanding spectrum of scn1a-related phenotype with novel mutations
Mutations in the genes encoding voltage-gated sodium channels cause a variety of epilepsy syndromes, with most of the mutations occurring in SCN1A gene. It is one of the most well-researched epilepsy genes. The SCN1A gene, which seems to be a relevant regulator of excitability of the CNS, is implicated in various epilepsy phenotypes through various genetic mechanisms ranging from common variants to rare monogenic variants. It is known that SCN1A gene is tightly linked to severe myoclonic epilepsy of infancy (SMEI). However, its phenotypic spectrum is expanding. Here, we report clinical and genetic findings of 10 patients with SCN1A mutations where two of them were found to have novel mutations. Our findings support understanding and updating knowledge on the correlation between phenotype distribution and location and type of mutations in SCN1A-related disorders.
Kamu Politikalarının Oluşturulmasında Sivil Toplum Kuruluşlarının Etkisi
Gunumuz siyasal sitemlerinde kamu politikalarinin belirlenmesi bir sureci ifade eder ki, bu sureci besleyen bircok aktor vardir. Bas aktor, siyasal iktidarlar olmakla beraber, baski gruplari, sivil toplum kurumlari, gonullu kuruluslar, sendikalar gibi bircok hukumet disi organizasyon, politika belirleme surecinde rol alabilmektedir. Bu politikalarin sekillenmesinde basta Anayasa olmak uzere genel mevzuat goz onune alindigi gibi, degisen dunya sartlari, artan ve cesitlenen kamu hizmetleri ve bunlara iliskin talepler, yeni politikalarin uretilmesini zorunlu kilmaktadir. Uretilen kamu politikalarin guclu, etkin ve cozum odakli olmasi icin sorunlarin dogru tespit edilmesi gerekir. Bunun icin de sorunlari yasayan paydaslarin surece dâhil edilmesine ihtiyac duyulur. Her ne kadar politika belirleme surecinde tum aktorler arasinda zimni bir rekabetin varligi hissedilse de, esas olan, surecin tek boyutlu olamayacaginin farkinda olmaktir. Bununla beraber, ulusal ve yerel siyasetten tutun da farkli duzeyde orgutlenmis tum organizasyonlarin politika yapma surecine ne duzeyde etki ettiklerinin arastirilmasi gerekmektedir. Bu calisma iste mevcut calismalar cercevesinde bu etki hakkinda bir takim degerlendirmeler yapmaktadir.