Incidence and prognostic significance of sustained ventricular tachycardias in heart failure patients implanted with biventricular pacemakers without a back-up defibrillator: results from the prospective, multicentre, Mona Lisa cohort study

The aim of this study was to investigate the 12-month incidence, predictive factors, and prognosis of sustained ventricular tachycardia (VT) in chronic heart failure patients implanted with biventricular pacemakers without a back-up defibrillator (CRT-P), assessed by continuous intracardiac ventricular electrograms.

Diagnosis and follow-up of Wegener's granulomatosis by cardiac magnetic resonance

International audienc

Premature foetal closure of the arterial duct: clinical presentations and outcome

The prevalence of intra-uterine ductal dysfunction is unknown and the clinical consequences are poorly understood. The aim of this study was to investigate the echocardiographic (ECHO) abnormalities and outcomes of this rare phenomenon.

A frozen heart

An 81-year-old woman was found unconscious on a walking path. The patient had severe hypothermia (central body temperature: 30°C). She was known to be insulin-dependent diabetic for many years and recently developed signs of dementia. Biological …

‘Valve-in-valve’ implantation in a patient with degenerated aortic bioprosthesis and severe regurgitation

A 70-year-old man was admitted due to dyspnoea (NYHA class III). In 1989, he underwent an aortic valve replacement using a Carpentier–Edwards bioprosthesis no. 21 and a left internal mammary artery–left anterior descending coronary bypass. In 2003, a laryngectomy and post-operative radiotherapy were performed because of laryngeal cancer. He then decided to stop smoking. …

Guidelines for the diagnosis and treatment of pulmonary hypertension: The Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT)

Journal ArticlePractice Guidelineinfo:eu-repo/semantics/publishe

Severe right bivalvular carcinoid heart disease

Rosiglitazone reduces ischaemia-reperfusion injury in patients with the metabolic syndrome

In animals, thiazolidinediones reduce ischaemia-reperfusion injury. A clinical meta-analysis raised suspicion that rosiglitazone increases the incidence of myocardial infarction (Nissen et al. , N Engl J Med 2007;356:2457–2471). However, human data on a possible benefit on infarct size (i.e. ischaemia-reperfusion injury) are not available. Therefore, we investigated the effect of rosiglitazone on ischaemia-reperfusion injury …

Effect of baroreflex stimulation using phenylephrine injection on ST segment elevation and ventricular arrhythmia-inducibility in Brugada syndrome patients

Patients affected by Brugada syndrome (BrS) are at risk of sudden cardiac death specifically at rest, when vagal tone is high. The aim of our study was to assess whether a phenylephrine injection, which provokes a baroreflex stimulation, could induce modification of the ST segment elevation and ventricular arrhythmias.

Pseudo-pacemaker syndrome in a young woman with first-degree atrio-ventricular block

First-degree atrio-ventricular (AV) block is defined as a PR interval longer than 200 ms. If too long, it can become clinically relevant and may mimic a pacemaker syndrome. We report the case of a young woman with a long PR interval, probably congenital, with episodes of syncope and dizziness since childhood. Pseudo-pacemaker syndrome is rare and is a Class IIa recommendation for a pacemaker implantation. A dual-chamber pacemaker was implanted and short AV delay was programmed, with rapid clinical improvement.