Evaluation and management of fungal risk in Cystic Fibrosis: first results of a national French study

175 Evaluation and management of fungal risk in Cystic Fibrosis: first results of a national French study S. Leroy1, V. Conseil1, B. Coltey2, Y. Lemeille2, S. Dominique3, G. Gargala3, P. Domblides4, I. Accoceberry4, G. Loeuille5, I. Durand-Joly5, A. Fanton6, O. Vagnier6, F. Dalle6, A. Boldron5, C. Llerena2, C. Pinel2, J.L. Ginies7, M. Pihet7, C. Person7, J. Bouchara7, N. Wizla1, C. Marguet3, L. Favenne3, S. Bui4, L. Delhaes1. 1CHRU, Lille, France; 2CHU, Grenoble, France; 3CHU, Rouen, France; 4CHU, Bordeaux, France; 5CHG, Dunkerque, France; 6CHU, Dijon, France; 7CHU, Angers, France

Clinical follow-up of 13 French CF patients with Inquilinus limosus

Sputum eosinophils are elevated in CF patients with asthma

Gallbladder dysfunction contributes to impaired bile salt homeostasis in cystic fibrosis

Actualité sur les effets de la vitamine D et l’évaluation du statut vitaminique D

P278 - Granulocyte macrophage colony stimulating factor improves mucosal repair in a mouse model of acute colitis

O10 ASSOCIATION BETWEEN IL23R, ATG16L1, IRGM AND NOD2 SUSCEPTIBILITY GENES AND SUBPHENOTYPES ON A LARGE COHORT OF IBD PATIENTS

P023 CROHN'S DISEASE PRESENTATION IN PEDIATRIC PATIENTS

P078 NUTRITIONAL STATUS AND GROWTH IN PEDIATRIC CROHN'S DISEASE (CD): A POPULATION BASED STUDY

RESULTS: At diagnosis, 25 children (9.5 % ) showed height < ! 2 s.d., 70 (27 % ) weight < ! 2 s.d., and 84 (32 % ) BMI < ! 2 s.d. At maximal follow-up, growth retardation was present in 18 children (6.9 % ) whereas 40 (15 % ) had malnutrition. Nutritional status was more severely impaired in children with stricturing disease. Growth and nutritional retardation at diagnosis, young age, male gender, and extraintestinal manifestations at diagnosis were indicators of poor prognosis. A signifi cant compen- sation was observed for weight and BMI in both genders and for height in girls. No treatment was associated with height, weight, or BMI at maximal follow-up. CONCLUSIONS: In a pediatric population-based study, growth retardation and severe malnutrition are still present at maximal follow-up in 6.9 and 15 % of CD children, respectively. Young boys with substantial infl am- matory manifestations of CD have a higher risk of subsequent growth failure, especially when growth retardation is present at diagnosis.

B011 Stimulus specific changes of energy metabolism in hypertrophied heart