Ethno-medicinal plants as potential sources for cervical cancer treatment

This study investigated the anticancer potential of three ethnomedicinal plants: Annona squamosa , Coccinia grandis , and Solanum nigrum , traditionally used for various ailments. While their efficacy against cancer remains largely unproven, this study aimed to explore their potential as anticancer agents. Extracts of plants were prepared using various solvents and their cytotoxic activity against SiHa (Human Papillomavirus HPV16) and HeLa (HPV18) cervical cancer cell lines was assessed using the CYQUANT ASSAY. A three-point primary screening was conducted with varying concentrations of extracts and a reference compound Puromycin.

Revolutionizing leather treatment with emulsified Chlorella vulgaris oil: a green fatliquor alternative

Fatliquors enhance the flexibility of leather. This study explores a sustainable alternative by utilizing waste-derived Chlorella vulgaris oil for fatliquoring applications. Initial biochemical analysis revealed a lipid content of 28.4% in C. vulgaris biomass, highlighting its suitability as a bio-based feedstock. GC-MS analysis showed the presence of palmitic, linoleic, and linolenic acids, with an iodine value of 102, indicating potential for improving softness, tensile strength, and moisture retention in leather. Chemical modifications via sulfation and transesterification showed stable emulsions with zeta potentials of −73.2 mv and −62.9 mv, and particle sizes of 126.51 nm and 99.16 nm, respectively. FTIR confirmed successful functionalization supporting emulsification, fiber binding, and lubrication. Experimental leathers treated with sulfated and transesterified oils showed significant improvements in softness (64.37%), elongation at break (58.65%), tensile strength (33.16%), and tear strength (up to 182.2%) compared to control leather fatliquored with Turkey red oil. SEM analysis further revealed well-lubricated and uniform fiber structures in treated leathers. Thus, fatliquors synthesized from waste algae offer a customizable, biodegradable, and non-toxic alternative to conventional fatliquors, supporting eco-friendly and high-performance leather processing. Future studies could optimize C. vulgaris oil modifications for different leather types and assess the scalability of this bio-based fatliquor for industrial applications.

On interlacing of net-Laplacian and normalized net-Laplacian eigenvalues of signed graphs

This paper explores the interlacing inequalities in the net-Laplacian eigenvalues of a signed graph Γ, and its subgraph$ \Gamma -F $ Γ − F , formed by removing$ Feq E(\Gamma ) $ F ⊆ E ( Γ ) . Using this, we obtained bounds for the number of negative and positive net-Laplacian eigenvalues of Γ. An inequality is derived between the net-Laplacian eigenvalues of Γ and$ \Gamma -U $ Γ − U , where$ Ueq V(\Gamma ) $ U ⊆ V ( Γ ) . Also, for a signed graph Γ, the net-Laplacian matrix is normalized, and an inequality is derived between the eigenvalues of the normalized net-Laplacian of a signed graph and its subgraph, formed by contraction of edges (vertices). Additionally, it is shown that replicating a vertex in a signed graph creates a net-Laplacian eigenvalues equal to the net-signed degree of the replicated vertex. The paper concludes by correcting the eigenvalue interlacing of normalized Laplacian matrices in vertex replication.

On the construction of trend free constant block sum PBIB designs

Agricultural and industrial experimentation may often witness the effect of systematic trend. Trend effects, though remote, may still influence the response under consideration. The incorporation of trend effects in the model thus paves the way for proper model specification. Completely trend robust block designs, which are commonly known as trend-free block designs, are an important class of block designs in such a way that the analysis can be done in the usual manner as it could be done in case of normal block designs due to orthogonal nature of trend effects and treatment effects. This article deals with the construction of some classes of completely trend robust i.e. trend free constant block sum partially balanced incomplete block (TFCBS-PBIB) designs along with characterization properties. SAS macros have also been developed and made available in public domain to provide readymade solutions to the end-users.

Maximum likelihood and Bayesian estimation of traffic intensity for a bulk-service queue with batch-size-dependent service mechanism

In this article, we provide two different estimates such as maximum likelihood and Bayesian estimates of the traffic intensity of a bulk-service queue with batch-size-dependent service as these systems have potential applications in manufacturing industries, supply chain management, telecommunication channels etc. Using the same, the total system cost can be optimized and it also improves the efficiency of the system. In the Bayesian setup, three prior distributions as well as two loss functions are incorporated. It also includes the regression analysis which generates a relationship between the parameter and the estimated values. The aforementioned methodologies are illustrated numerically and graphically by employing simulation method.

On general weighted extropy of extreme ranked set sampling

The extropy measure, introduced by Lad, Sanfilippo, and Agro in their (2015) paper in Statistical Science, has garnered significant interest over the past years. In this study, we present a novel representation for the weighted extropy within the context of extreme ranked set sampling (ERSS). Additionally, we offer related findings such as stochastic orders, characterizations, and precise bounds. We study the results of ERSS on cumulative past extropy and conduct a comparative analysis between the extropy estimator in ERSS and simple random sampling (SRS) using simulation method. Our results shed light on the comparison between the weighted extropy of ERSS and its counterpart in SRS.

Practices Adopted by the Faculty to Increase Research Impact, Visibility, and Citations of Their Research Work: A Case Study of the Two Indian Universities

The Northern Universities in Odisha, India, are home to a diverse group of faculty who are engaged in cutting-edge research in a wide range of fields. However, to ensure that their research work has a greater impact, visibility, and citation, these faculty adopt various practices. This case study delves into the practices adopted by faculty in the northern universities of Odisha to greater the impact of their study. This study looks at how faculty use social media, scholarly communication platforms, and academic networks to share their research findings. It also examines how other methods for disseminating knowledge, such as open access publishing, may boost the effect of the research. The usage and awareness of various strategies by faculty at northern universities in Odisha to increase the visibility, significance, and citations of their research piece is also examined in this study. In conclusion, this case study provides insights into the various practices adopted by the faculty in northern universities of Odisha to improve their research’s impact, visibility, and citation. It highlights the importance of adopting a multi-pronged approach to research dissemination, which involves using a combination of social media, scholarly communication platforms, and academic networks. The findings of this study could serve as a useful resource for Faculty, researchers, and policymakers seeking to increase the impact and visibility of their research work. Librarians can use the findings to improve research support services, enhance institutional repositories, and organize workshops on citation management and visibility strategies. University administrators and policymakers can develop supportive policies, refine performance evaluation metrics, and allocate resources to initiatives that promote research visibility. Overall, this study provides actionable strategies for building a more inclusive and efficient scholarly communication ecosystem.

Zirconia Enriched BaO-SiO 2 -TiO 2 Glasses with Enhanced Physical, Mechanical and Biological Performances

Zirconia doped glasses are ideal for biomedical applications owing to their improved mechanical strength, non-toxicity and biocompatibility. Herein, ZrO 2 doped BaO-SiO 2 - TiO 2 (BST) based glasses within the system (30– x )BaO.40SiO 2 .30TiO 2 . x ZrO 2 (0≤x;≤6) were fabricated using a melt-quenching technique. X-ray diffraction (XRD) measurements confirmed the non-crystalline nature of the glass samples. Density of the glasses increased from 3.538 to 3.802 g/cm 3 . Fourier transform infrared (FTIR) spectroscopy was employed to examine the structural or bonding mechanism. Further, mechanical performance of the glass pellets was studied using a universal testing machine (UTM) in compression mode, showing that the compressive strength increased with higher ZrO 2 content, from 20.4 to 222 MPa of the glasses. Cell viability using 3-(4,5-dimethyl-2- yl)-2,5-diphenyltetrazolium bromide (MTT) assays on the human osteoblastic cell line (MG-63) revealed no cytotoxic effects on osteoblast cells, and maintaining cell viability even at higher concentrations. Additionally, cell cytotoxicity was evaluated using trypan blue assay and DAPI (4,6-diamidino-2-phenylindole) staining on glass samples. Therefore, the present study uniquely demonstrates that systematic ZrO 2 incorporation into BaO-SiO 2 -TiO 2 glass matrices markedly enhances both mechanical strength and biological activity, establishing a new class of bioactive glass compositions with simultaneous structural and biomedical advantages for bone regeneration applications.

New national and regional bryophyte records, 80

New national and regional bryophyte records, 82