Microstructure evolution of AlSi10Mg alloy in RAP process

With its computer-aided layer-by-layer production approach, additive manufacturing (AM) and powder bed laser fusion (PBLF) paved the way to produce metallic parts more precisely than any other manufacturing technique. However, the combinability and the interaction of this relatively new manufacturing technique with the other near-net shape production techniques is still a mystery. In this study, the recrystallization and partial melting (RAP) behavior, which is a feedstock production approach for semisolid forming methods, investigated on AlSi10Mg parts produced by PBLF and conventional casting were compared in terms of microstructural and hardness evaluations. After the reheating process, the globalization of Si particles and the breakdown of the Si network around the melt pools were displayed with light microscope and scanning electron microscope (SEM) images. The hardness values of the PBLF as-fabricated specimens were found to be significantly higher than the as-cast specimens; however, the values were almost equaled after the RAP treatment and even got lower on the bottom and top regions of the PBLF samples after 20 min of reheating because of the enlarged shrinkage porosities and the coarsened morphology.

In vitro and in silico investigations of the pro-apoptotic activity of Opuntia ficus-indica cladode extracts against K562 cells

Unveiling the link: Helicobacter pylori infection and impact on ischemia modified albumin, thiol, and disulfide levels

Novel benzene sulfonamide-piperazine hybrid compounds: design, synthesis, antioxidant, enzyme inhibition activities and docking, ADME profiling studies

Benzene sulfonamides are an important biological substituent for several activities. In this study, hybridization of benzene sulfonamide with piperazine derivatives were investigated for their antioxidant capacity and enzyme inhibitory potencies. Six molecules were synthesized and characterized. DPPH, ABTS, FRAP, CUPRAC, chelating and phosphomolybdemum assays were applied to evaluate antioxidant capacities. Results show that compounds have high antioxidant capacity and compound 4 has the best antioxidant activity among them. Compound 4 has higher antioxidant activity than references for FRAP (IC 50 : 0.08 mM), CUPRAC (IC 50 : 0.21 mM) and phosphomolybdenum (IC 50 : 0.22 mM) assays. Besides this, compound 4 has moderate DPPH and ABTS antioxidant capacity. Furthermore, enzyme inhibition activities of these molecules were investigated against AChE, BChE, tyrosinase, α -amylase and α -glucosidase enzymes. It was revealed that all compounds have good enzyme inhibitory potential except for α -amylase enzyme. The best inhibitory activities were observed for AChE with compound 5 the same value (IC 50 : 1.003 mM), for BChE with compounds 2 and 5 the same value (IC 50 : 1.008 mM), for tyrosinase compound 4 (IC 50 : 1.19 mM), and for α -glucosidase with compound 3 (IC 50 : 1.000 mM). Docking studies have been conducted with these molecules, and the results correlate well with the inhibitory assays.

GD23133-SOĞUK PLAZMA TEKNOLOJİSİ VE MEYVE, SEBZE, ET, TAVUK VE SU ÜRÜNLERİNDEKİ UYGULAMALARI

The Effect of Plyometric Exercises Using the Cluster Set Method on Certain Physical and Physiological Parameters in Female Handball Players

Farklı Uyruklardan Öğrencilerin Uyum Sınıfında Bireysel ve Kültürel Farklılıklardan Kaynaklanan Sorunları Hakkındaki Öğretmen Görüşleri

OKUL ÇAGINDA YÜRÜYEBİLEN SPASTİK BİLATERAL SEREBRAL PALSİLİ ÇOCUKLARDA DENGE DURUMLARI KATILIM KISITLILIĞI İLE İLİŞKİLİ MİDİR?

Pediatric Bobath Concept in the Management of Children with Cerebral Palsy: The View of Turkish Bobath Therapists

A survey of the prevalence and genotypes of Cryptosporidium spp. and Giardia duodenalis in shelter dogs in Batman, Turkey