Brexit and the Emergence of a Transnational European Community of Practice: From Grassroots Mobilisations to Supranational Political Opportunity Structures in the Struggle for Citizens' Rights

Abstract Brexit ignited an unprecedented sense of shared European identity and belonging, catalysing pro‐EU social movements among EU nationals in the United Kingdom and amongst British citizens residing in the EU and leading to the formation of a transnational European community of practice. This mobilisation coalesced around grassroots organisations whose claim‐making strategy was rooted in the institution of EU citizenship, which also grounded their legitimacy. Drawing on a relational approach to diasporic and transnational social movements, mixed methods empirical research including the findings of an online survey of mobile citizens ( n  = 1919), archival and documentary analysis, expert interviews and policy analysis, the article analyses the significance of supranational political opportunity structures to the emergence of a transnational European community of practice during Brexit and the formation of an alliance between two of the primary grassroots organisations advocating for citizens' rights – the3million and British in Europe.

Executive function predicts academic and social skills in autistic kindergartners based on a multimodal approach

Background Executive functions (EF) are cognitive processes that underlie goal‐directed abilities and behaviors which have been found to be variable in autistic children. While EFs are well‐established predictors of academic and social outcomes in neurotypical children, it is unclear if these same associations are true for children with autism spectrum disorder (ASD). This study examined the relation between EF and academic and social skills in cognitively able, verbal kindergarteners with ASD, while using a multimeasurement approach to EF skills. Methods Participants included 67 autistic children aged 4–6 years longitudinally followed from kindergarten entry to exit. Children's EF was measured using a multimodal assessment approach with a computerized EF battery, behavioral observation, and parent report. Academic achievement and social skills were evaluated through a standardized assessment and parent report, respectively. Multiple regression models were conducted to explore the associations of EF with academic and social outcomes, while controlling for key demographic factors (e.g. age, sex, nonverbal IQ). Results EF, measured through the computerized battery, was significantly associated with math achievement when controlling for age, sex, and nonverbal IQ, both concurrently and longitudinally. EF difficulties, as reported by parents, were closely linked to current and later parent‐reported peer play challenges. Conclusions These findings indicate that EF may be critical foundational skills for school success in young autistic children at school transition. Therefore, targeted EF interventions could be a powerful way to optimize academic and social development in autistic kindergarteners. The results also highlight the importance of a multimeasurement approach to EF assessment, as it provides a more comprehensive understanding of the broader impact of EF on key developmental outcomes in ASD.

Prevalence of comorbidity amongst people with palmoplantar pustulosis: A systematic review and meta‐analysis

Response to ‘Cardiovascular and thromboembolic risks of JAK inhibitors in atopic dermatitis: A global cohort study’

From reactive to predictive: Advancing biologic dosing in dermatology

Abstract Biologic therapies are targeted immunomodulators that have revolutionised the treatment of chronic inflammatory dermatoses, including psoriasis, hidradenitis suppurativa and atopic dermatitis, offering high efficacy and safety for moderate‐to‐severe disease. However, standardised dosing regimens fail to account for inter‐individual heterogeneity, leading to non‐optimal drug exposure in certain patients. This may, in part, explain why primary non‐response, secondary loss of response or adverse effects are observed in real‐world practice. While empirical off‐label adjustments are commonly employed, data‐driven dosing optimisation may enable better disease control and reduce the burden of lifelong biologic treatment by avoiding excessive dosing. Therapeutic drug monitoring (TDM) involves adjusting doses based on serum drug concentrations to maintain therapeutic ranges, relying on established dose–exposure–response correlations. Although TDM provides reactive or proactive optimisation approaches, its threshold‐based adjustments are limited by an inability to predict individual pharmacokinetic variability or future clinical outcomes. Model‐informed precision dosing (MIPD) represents an evolution beyond conventional TDM by integrating population pharmacokinetic–pharmacodynamic models, patient‐specific characteristics and Bayesian forecasting to deliver personalised, adaptive dosing recommendations. This approach captures inter‐individual variability while linking serum drug concentrations to clinical response, enabling proactive dose adjustments using sparse or non‐steady‐state data. Emerging digital tools, point‐of‐care testing and integration of pharmacogenomics and biomarker profiling are expected to enhance MIPD’s precision and accessibility. Once implemented in routine care, MIPD has the potential to transform biologic therapy dosing using a dynamic, patient‐centric system that maximises clinical response, minimises overtreatment and supports sustainable healthcare delivery.

Messages for ultraviolet‐radiation protection to fair‐skinned populations

Abstract Background Skin cancer prevention remains a critical public health challenge, particularly in fair‐skinned populations in Europe, the United States and Australia, where incidence rates of keratinocyte skin cancer and melanoma continue to rise despite decades of public education on ultraviolet‐radiation (UVR) protection. Although progress has been observed in Oceania, the overall effectiveness of current prevention strategies remains insufficient. This paper aims to refine and disseminate more effective UVR protection messages by developing an evidence‐based, internationally adaptable public education leaflet. Methods The development of this educational material followed the current guidelines for the development of health promotion materials and effective public education. Based on the scientific evidence, a plain‐language message has been drafted. It was subsequently revised through multiple rounds of multi‐stakeholder feedback from dermato‐oncology, epidemiology, public health experts, patient organizations representatives and NGOs involved in prevention and health promotion. Results The final educational leaflet emphasizes three core messages: avoiding intentional sun exposure and tanning, utilizing shade and protective clothing as primary UV protection strategies and using sunscreen as a supplementary protective measure. Additional recommendations address childhood sun protection, the dangers of tanning beds and the importance of monitoring skin for early signs of cancer. Common concerns such as vitamin D synthesis and sunscreen safety are also addressed with evidence‐based responses. Discussion This initiative highlights the necessity of shifting public attitudes towards UVR exposure and developing tailored, culturally sensitive communication strategies. The freely available leaflet will be distributed through professional associations and online platforms. Future efforts should involve policymakers in implementing structural changes, such as enhancing public shade availability and regulating tanning facilities, to promote long‐term behavioural shifts in UV protection.

Engagement and retention with remote monitoring in psoriasis: Findings from the mySkin study

Avoiding methodological pitfalls in assessing cardiovascular and thromboembolic risk in dermatology

NPWT in skin transplantation: Promising, but is the jury still out?

Long‐term safety and efficacy in paediatric psoriasis: Remaining challenges