It is unknown whether endovascular thrombectomy (EVT) is cost effective in large ischemic core infarcts.
One of the key challenges arising when compilers vectorize loops for today’s SIMD-compatible architectures is to decide if vectorization or interleaving is beneficial. Then, the compiler has to determine the number of instructions to pack together and the interleaving level (stride). Compilers are designed today to use fixed-cost models that are based on heuristics to make vectorization decisions on loops. However, these models are unable to capture the data dependency, the computation graph, or the organization of instructions. Alternatively, software engineers often hand-write the vectorization factors of every loop. This, however, places a huge burden on them, since it requires prior experience and significantly increases the development time. In this work, we explore a novel approach for handling loop vectorization and propose an end-to-end solution using deep reinforcement learning (RL). We conjecture that deep RL can capture different instructions, dependencies, and data structures to enable learning a sophisticated model that can better predict the actual performance cost and determine the optimal vectorization factors. We develop an end-to-end framework, from code to vectorization, that integrates deep RL in the LLVM compiler. Our proposed framework takes benchmark codes as input and extracts the loop codes. These loop codes are then fed to a loop embedding generator that learns an embedding for these loops. Finally, the learned embeddings are used as input to a Deep RL agent, which dynamically determines the vectorization factors for all the loops. We further extend our framework to support random search, decision trees, supervised neural networks, and nearest-neighbor search. We evaluate our approaches against the currently used LLVM vectorizer and loop polyhedral optimization techniques. Our experiments show 1.29×−4.73× performance speedup compared to baseline and only 3% worse than the brute-force search on a wide range of benchmarks.
Recurrent spontaneous abortion (RSA) is a problem that faces women for a variety of reasons. Although leiomyomata is relatively common, calcified leiomyomata which is called “womb stones” is a very rare cause of RSA. These womb stones are correlated with retained products from conception and osseous metaplasia. We report a very rare case of a large calcified leiomyomata which caused secondary infertility and pregnancy loss of 7 pregnancies due to spontaneous abortions.
In this paper, we show that a sequence satisfying a Suzuki-type JS-rational contraction or a generalized Suzuki-type Ćirić JS-contraction, under some conditions, is a Cauchy sequence. This paper presents some common fixed point theorems and an application to resolve a system of nonlinear fractional differential equations. Some examples and consequences are also given.
Protection relays design and manufacture have arrived to a new level of advancement; hence, numerical relays have appeared recently. They combine all the functions of monitoring, control, and protection in one device. Also these relays have the ability to communicate with each other to share statuses and orders using GOOSE (generic object‐oriented substation events) messages based on communication protocols such as IEC61850. In this paper, a proposed method for overcurrent (OC) relay coordination has been introduced based on numerical relay features of several setting groups and communication capability. This work supposes that the coordination between feeder, bus section, and incomer protection relays, in a substation of single busbar configuration with bus sectionalizer (i.e., bus section), depends on the status of the bus section circuit breaker (CB) as a criterion for determining active relay setting group, to achieve a faster tripping action. ETAP has been used as a simulation software environment. And the simulation results show the advantages of the proposed method in reducing the time needed by the relay to clear the electrical fault. Siemens SIPROTEC series have been used as an example of numerical relays, specifically 7SJ64 as OC relay, which exists in the ETAP library.
Background. Allergic rhinitis (AR) is a global disease that affects a huge proportion of people around the world especially in the Middle East, where multiple allergy-promoting factors can be found. Although AR is not fatal, it severely affects the quality of life. However, it is usually overlooked in developing countries due to resource scarcity. Methods. An online questionnaire on social media was used which included demographics, smoking, socioeconomic-status (SES), war-related questions, and the score for allergic rhinitis (SFAR), a simple self-reporting tool with the cut-off point at 7. Findings. This study included 968 subjects with 721 (74.5%) females. The mean age was 24.69 years with AR prevalence at 47.9%. AR was associated with male gender [P=0.001 (OR, 1.677; 95% CI 1.249-2.253)], having a job [P=0.049 (OR, 1.309; 95% CI 1.001-1.713)], the having a chronic medical condition (P0.05). Interpretation. Approximately half of the sample displayed AR symptoms, indicating a potentially high burden of AR in the community. A correlation to being distressed from war noises was found with AR which could reflect a psychological aspect. In addition, in war harmful allergens are released which can be an additional AR risk factor which adds to the environment in the Middle East that is associated with AR. However, we need further studies to discover and minimize this huge prevalence of AR.
Acute lymphoblastic leukemia (ALL) is a common malignancy in children. Consanguinity has a high prevalence in developing countries and increases the probability of homozygosity for many genes which may affect ALL and its prognosis. We conducted a study to explore the impact of consanguinity and number of siblings on ALL as there are currently no studies to describe this effect. Data were collected from patients’ records from the Children’s University Hospital of Damascus University, which is the major cancer centre for children in Syria. This study included 193 children with ALL over one year. Number of siblings was not with the French–American–British (FAB) classification, gender, ALL subtype, or risk of ALL children. When comparing consanguinity degrees and complete blood counts at diagnosis, significant contradicting data were found in the third-degree and fourth-degree consanguinity when compared to one another and to not having consanguineous parents as third degree consanguinity was associated with normal platelets but lower WBC counts, and fourth-degree consanguinity was associated with normal haemoglobin levels and WBC counts, but lower platelet counts. Having consanguineous parents was also associated with acquiring ALL at an older age, L2 FAB classification, having a positive family history for malignancies, and not having hepatosplenomegaly (P0.05). Although consanguinity and number of siblings have affected some variables and prognostic features of childhood ALL, the aetiology is not clear and we need further studies to clarify such an association as this will help in optimising therapy and accurately determine the risk.
The aim of this paper is to obtain the common fuzz fixed points of α-fuzzy mappings satisfying generalized almost Y,Λ-contraction in complete metric spaces. Our results are extensions and improvements of the several well-known recent and classical results in literature. We give an example for supporting these results. As an application, we apply our obtained results to study the existence of a solution for a second order nonlinear boundary value problem.
Lymphangiomas are benign tumours of lymphatic vessels which are not linked with the normal lymphatic vessels. Their symptoms usually depend on their location and size as they can compress or block adjacent organs. We present a 9-month-old girl with isolated cavernous lymphangiomas of the spleen, a rare variable of lymphangiomas, with no symptoms. She had an isolated anaemia which could only be explained by the hypersplenism caused by the lymphangiomas. Such a presentation has been very rarely reported in the literature and not mainly in children. Furthermore, this case also illustrates imaging of hypersplenism related to lymphangiomas.