Journals
2026 EN
Du Boyu · Zhang Jiajun · Yang Yuxin
+6 more
ABSTRACT With the continuous advancement of social technology and the increasing awareness of health management, biomass‐based triboelectric nanogenerator (TENG) displayed significant potential as flexible wearable electronics for continuous foot gait monitoring. Nevertheless, existing biomass‐based TENG often faces challenges of insufficient mechanical robustness and durability in practical applications, where they are prone to surface abrasion and structural fracture under continuous compression and friction, severely limiting their long‐term performances. In order to address these challenges, this work proposed a multiscale crosslinking strategy, which strengthened the noncovalent interactions within the polymer by constructing multiple reinforcement networks, successfully fabricating a dual‐network C─lignin‐based triboelectric material (CLTM) with excellent durability and crack resistance. Among them, the optimal CLTM (PSGCL‐0.2) exhibited high mechanical strength (strain 445%, tensile strength 41.56 MPa, Young's modulus 41.25 MPa, toughness 159.67 MJ/m 3 ) and excellent cyclic stability (300 cycles) with versatile functionalities, including antibacterial, antioxidant, and UV‐shielding properties, water stabilization (255.51 g/m 2 /d), efficient photothermal conversion, and full recyclability. Furthermore, biomass‐based TENG device assembled from PSGCL‐0.2 achieved stable triboelectric output properties (102.5 V, 2.9 µA, and 61.3 nC), and sustainable for 2000 cycles, fast response time (68 ms), and excellent power density (325.9 mW/m 2 ), effectively converting mechanical energy into electrical energy. Especially, PSGCL‐0.2 was also integrated into the wireless self‐powered smart insole, successfully enabling real‐time visual monitoring of plantar pressure distribution and dynamic gait. Meanwhile, combined with the machine learning algorithm, the self‐powered smart insole achieved precise recognition and classification of eight different motion states with an accuracy of 98%. This study provides the feasible strategy for developing extremely stable and durable biomass‐based TENG, aimed at advancing sustainable intelligent healthcare systems.
Journals
2026 EN
Tanaka Takuya · Koyanagi Hirosato · Ehara Takumi
+6 more
ABSTRACT Aggregation‐induced emission luminogens (AIEgens) are typically large π‐conjugated molecules, but their low affinity and noninvasiveness toward analytes limit practical applications. To address this, smaller, more planar AIEgens are needed. Stilbene, though structurally suitable, lacks visible luminescence. Here, we report a minimally modified stilbene‐based AIEgen—4‐dipropylamino‐4’‐cyano‐bridged stilbene ( DpCBS[7] )—that exhibits fluorescence solvatochromism and efficient AIE across a broad polarity range in the visible region. DpCBS[7] exhibits low quantum yields ( Φ fl = 0.01–0.04) in solvents from nonpolar n ‐hexane to polar dimethyl sulfoxide, with large Stokes shifts, viscosity‐sensitive luminescence, and highly efficient solid‐state luminescence ( Φ fl = 0.70). To elucidate its dual solvatochromic and AIE behavior, femtosecond transient absorption spectroscopy was conducted. In solution, DpCBS[7] displays transient absorption with lifetimes of 21 ps (toluene) and 56 ps (acetonitrile) at 293 K, indicating ultrafast nonradiative decay leading to low Φ fl . Arrhenius analysis over the temperature range of 263–313 K revealed activation energies (Δ E a ) of 9.90 kJ/mol in toluene and 12.8 kJ/mol in acetonitrile for the S 1 → S 0 decay of DpCBS[7] . The Δ E a values show no clear systematic dependence on solvent polarity. In contrast, pre‐exponential factor A remains consistently high regardless of solvent polarity, indicating that the striking photophysical response is governed primarily by the pre‐exponential factor rather than by modulation of the activation energy. These findings highlight the fundamental importance of tailoring the distribution function through structural modification as a robust strategy to control AIE characteristics.
Journals
2026 EN
Zhou Zhenjie · Wang Huizhong · Yao Junxiong
+8 more
ABSTRACT Organic room‐temperature phosphorescent (RTP) materials, characterized by their prolonged emission durations, cost‐effectiveness and environmental sustainability, present substantial potential for utilization in optoelectronic devices and information encryption, thereby garnering considerable research attention. Nevertheless, the intrinsically weak spin–orbit coupling (SOC) in organic molecules hampers efficient intersystem crossing (ISC) between singlet and triplet states, thereby shortening the lifetime ( τ ) of RTP. Achieving room‐temperature phosphorescence in organic molecules hinges on overcoming two fundamental challenges: promoting efficient ISC between singlet and triplet states and suppressing non‐radiative decay through rigid microenvironmental confinement. This review summarizes recent advances in pure organic RTP from the perspective of multicomponent systems, highlighting emerging strategies for modulating exciton dynamics and rigidifying the local environment of emissive molecules. Approaches such as supramolecular self‐assembly, guest–host doping, eutectic formation and exciplex engineering are discussed as effective means to suppress non‐radiative deactivation and realize ultralong RTP (emission lifetime of over 100 ms). The underlying design principles and representative applications of these systems are delineated, and future directions for constructing high‐performance pure organic RTP materials are outlined. Our goal is to foster interdisciplinary collaboration and innovation to fully exploit the potential of RTP materials in organic optoelectronics and biomedicine. This review aims to delineate a coherent research trajectory and offer forward‐looking insights into emerging opportunities in this rapidly evolving field. By promoting cross‐disciplinary dialogue to catalyze new ideas and applications that harness the unique photophysical characteristics of RTP materials for transformative technological advancements.
Journals
2026 EN
Yang Xinzhe · Kang Miaomiao · Wang Dong
+1 more
ABSTRACT The resulting product of biocoupling is a bioconjugate, typically formed by linking molecules to proteins, oligosaccharides, nucleic acids, or synthetic polymers. By conjugating fluorescent probes with bioactive molecules via click chemistry or bioorthogonal reaction, functional materials with high specificity, sensitivity, and accuracy can be developed. A particularly promising strategy involves the use of aggregation‐induced emission (AIE) fluorophores, which exhibit augmented luminescence intensity and excellent photostability when in the aggregated state, making them especially suitable for bioimaging and biosensing applications. The rapid expansion of AIE active bioconjugates now calls for a comprehensive review to summarize and systematize recent advances. In this review, we direct our focus toward the biosensing, bioimaging, and therapeutic applications of AIE active bioconjugates prepared via click chemistry or bioorthogonal reactions. We anticipate that this overview will promote the development of versatile AIE bioconjugates and inspire further innovations in bioorthogonal chemistry for biomedical applications.
Journals
2026 EN
Iida Yuuto · Gon Masayuki · Yoshida Hiroyuki
+2 more
ABSTRACT Circularly polarized luminescence (CPL) has attracted considerable attention owing to its wide range of potential applications. Cholesteric liquid crystals (CLCs) are promising candidates for CPL‐active materials because of their ease of fabrication, stimulus responsiveness, and ability to achieve high dissymmetry factors (| g lum |). In most studies on CPL‐active CLCs, non‐mesogenic luminophores are doped into commercially available liquid crystals (LCs). However, their low solubility in LCs (typically only a few wt%) and their tendency to disrupt LC alignment present challenges in achieving high | g lum | values—particularly in thin cells—and in broadening the CPL spectra. Here, we report a new LC mixture comprising our previously designed mesogenic fluorophore and a commercially available LC. This strategy enables a markedly increased luminophore loading (up to ∼50 wt%) and enhances the birefringence of the LC matrix. As a result, we achieved a notably high | g lum | value of 1.25 even in thin cells (2 µm), together with significantly broadened CPL spectra. Furthermore, the emission wavelength was successfully tuned via Förster resonance energy transfer. This work demonstrates a rational design strategy for LC mixtures that yield CPL materials with high | g lum |, advances the fundamental understanding of CPL generation in photoluminescent CLCs, and highlights their potential for future photonic and optoelectronic applications.
Journals
2026 EN
Chen Guoqiang · Wang Lin · Chen Yameng
+6 more
ABSTRACT Ischemic stroke inflicts severe neurological damage by disrupting the neurovascular unit. While promising, mesenchymal stem cell (MSC) therapies are hampered by poor posttransplantation survival and nonspecific secretomes. Here, we introduce a bioengineering strategy that employs cadherin‐functionalized interfaces to generate cohesive multicellular MSC aggregates (Cad‐MAs). Priming MSCs with recombinant N‐cadherin and VE‐cadherin stimulated endogenous cadherin expression and facilitated the self‐assembly of stable spheroids with reinforced intercellular adherens junctions. Cad‐MAs exhibited increased resistance to inflammatory stress and anoikis, and secreted a reparative profile enriched in neurotrophic and angiogenic factors, as well as exosomes carrying therapeutic miRNAs such as miR‐21‐5p and miR‐126‐3p . The in vitro analyses indicate that cadherin‑empowered assembly yields MSC aggregates in which structural stability is coupled with a pro‑survival, pro‑regenerative phenotype. Furthermore, in a mouse stroke model, systemically delivered Cad‑MAs significantly outperformed conventional dissociated MSCs, promoting functional recovery, reducing infarct volume, and improving cerebral perfusion alongside evidence of enhanced angiogenesis and preservation of blood–brain barrier integrity markers. This approach, termed functional aggregation‑induced emergence (F‑AIE), provides a versatile framework for engineering integrated cellular therapeutics with tailored functional outputs for regenerative applications.
Journals
2026 EN
Chen Lifei · Yan Xuetao · Li Tianliang
+6 more
ABSTRACT Circularly polarized luminescence (CPL) materials, which exhibit their unique chiroptical properties, display great potential for applications in optoelectronics and bioimaging. However, it remains a significant challenge to synthesize CPL materials with high dissymmetry factors (g lum ) and photoluminescence quantum yields (PLQY) simultaneously. Herein, we report a deep‐eutectic‐solvent (DES)‐assisted self‐assembly protocol integrated with an active‐learning (AL) framework that enables the targeted fabrication of G‐quadruplex (G4) supramolecular gels with high g lum and PLQY. AL pinpointed the optimal synthesis parameters in just four iterations, dramatically accelerating material development. The top‐performing gel achieved a g lum of 0.29, setting a new benchmark for nucleoside/nucleotide‐based CPL materials. The maximum PLQY reached 10.64%, which represents a substantial level of performance. Furthermore, by integrating SHapley Additive exPlanations (SHAP), we elucidated the relationship between reaction parameters and target properties. Building on this result, we also demonstrated multicolor fluorescence resonance energy transfer (FRET) by incorporating dyes, successfully developing a series of multicolor CPL‐active materials. This work not only provides new insights into the design of bio‐based chiral CPL materials but also highlights the promising role of artificial intelligence in advancing material development.
Journals
2026 EN
Liu Hao · Liao Lingwen · Gu Wanmiao
+6 more
ABSTRACT Although metal nanoclusters (NCs) are ideal building units, significant challenges remain in manipulating their gathering and tuning the as‐obtained aggregate properties. Herein, we introduce an electro‐driven strategy and reveal the voltage‐dependent assembly on interdigitated microelectrodes based on Au 25 NCs: crystallizing at 0.5 V, NC‐based filming at 1.3 V, and nanocrystal‐based filming at 2.6 V. More interestingly, the film formed at 2.6 V can be varied from an insulator to a conductor, and even such a large conductivity tunability (from ∞ to ∼0.3 Ω) can be extended to the films formed from some other metal NCs such as Ag 25 , Pt 23 , and Pd 8 . The as‐obtained films show novel, promising properties not found in molecular NCs, as illustrated by the electrothermy and current‐limiting properties. Thus, this work not only provides a novel strategy for metal NCs’ gathering but also pioneers metal NC‐based electro‐manufacturing for novel findings and potential applications.
Journals
2026 EN
Di Haiting · Zhou Yi · Han Han
+9 more
ABSTRACT Metal–organic cages (MOCs) are versatile supramolecular platforms, but their modest binding affinities in aqueous solution limit practical utility. Chiral MOCs with enhanced binding capabilities are highly desirable for diverse applications, yet their synthesis remains challenging. Here, we report an “Axial‐Chiral Vertex Integration” (ACVI) strategy, which enables the construction of an enantiopure chiral cage ( MOC‐2 ) from a non‐chiral Pd 6 L 4 MOC ( MOC‐1 ) by substituting two axial Pd vertices with axially chiral BINOL units. This design strengthened the hydrophobic effect of the confined cavity, delivering ultrahigh aqueous binding affinity (up to 10 9 M −1 ) for MOCs. At the same time, the integration of a well‐defined chiral microenvironment endows MOC‐2 with notable enantioselectivity (up to 9.2) and the ability to transfer chirality to achiral guests, producing significant circularly polarized luminescence (| g lum | up to 10 −3 ). This strategy provides a powerful blueprint for designing high‐affinity chiral MOCs, unlocking opportunities in molecular recognition and advanced chiral functional materials.
Journals
2026 EN
Wang Xinyuan · Ji Shurui · Zhu Moshuqi
+2 more
ABSTRACT Optoelectronic technology plays a pivotal role in energy conversion, information processing, and bioanalysis, where efficient transduction between optical and electrical signals critically depends on materials with strong light absorption, rapid electronic response, and well‐controlled optical properties. Chiral metal nanoclusters (NCs), distinguished by their molecular‐level structural precision, high photostability, and hierarchical chirality reminiscent of biomolecular architectures, have emerged as promising candidates for optoelectronic applications, in which the multilevel origins of chirality—from the metal core to the metal–ligand (M–L) interface and surface ligands—provide effective means to tailor chiroptical properties and enable enantioselective luminescence and sensing platforms. This review provides a systematic overview of the structural origins, synthetic strategies, and optoelectronic applications of chiral metal NCs. The discussion outlines the multilevel origins of chirality in NCs architectures, followed by recent advances in enantioselective synthesis. Subsequent sections focus on their applications in chiral sensing, circularly polarized luminescence (CPL), and the emerging opportunities in chiral electrocatalysis inspired by the chiral‐induced spin selectivity (CISS) effect. The insights summarized here aim to guide the rational design of chiral metal NCs and to advance their integration into optoelectronic systems with enhanced chiral functionality.