Journals
2026 EN
Darvishmotevali Mahlagha · Gaan Niharika · Prentice Catherine
Drawing on social learning and social identity theories, this study examines how perceived managers’ values (transcendence vs. enhancement) and employees’ self-identity influence green voice behavior. Data were collected from employees in 4- and 5-star hotels. A three-wave data collection was adopted to minimize common method bias. The results show that perceived managers’ transcendence values positively impact employees’ green voice behavior, partially mediated by employees’ green self-identity. This mediation is stronger for male employees, whose self-identity plays a key role in driving voice behavior. This study offers novel insights by emphasizing the critical role of managers’ values in shaping employees’ environmental behaviors through identity reinforcement, addressing a gap in the literature on leadership and sustainability in the tourism and hospitality industry. Practically, the findings suggest that managers adopt transcendence values, such as environmental concern and social responsibility, to foster sustainability, enhance employee participation in green practices, and improve environmental performance and organizational reputation.
Resource
2026 EN
Sims Gary P. · Scaletta Lacie · Andrews John
+24 more
Anti-citrullinated protein autoantibodies promote inflammation and joint tissue injury and define a poor prognostic group of patients with rheumatoid arthritis (RA). Citrullinated autoantigens that drive this autoimmune response are generated by peptidylarginine deiminase (PAD) enzymes, which are predominately expressed and released by neutrophils and monocytes. Accordingly, blocking the enzymatic activity of PADs to curb the generation of citrullinated autoantigens that drive autoimmunity and tissue injury may provide therapeutic benefit. Herein, we developed a high affinity, bispecific, anti-PAD2/4, effector-null antibody, AZD1163, which potently inhibits recombinant PAD2 and PAD4 activity in both histone H3 and fibrinogen citrullination assays. AZD1163 inhibited all endogenous PAD activity in the serum of patients with RA irrespective of the presence of anti-PAD4 autoantibodies, and neutralized PAD activity in synovial fluid. AZD1163 also bound and internalized PADs expressed on cell membranes into low pH endosomes for degradation, reducing the surface expression and catalytic potential. Binding of AZD1163 to neutrophils and monocytes did not trigger complement-dependent cytotoxicity, antibody-dependent cellular cytotoxicity, or the production of proinflammatory cytokines, or otherwise impact neutrophil phagocytosis, production of reactive oxygen species, or NETosis. In a non-human primate study of pharmacokinetics (PK) and pharmacodynamics, a single dose of AZD1163 exhibited PK consistent with a half-life extended antibody and a rapid and durable suppression of endogenous PAD activity. AZD1163 has a favorable preclinical safety profile. Collectively, these in vitro and in vivo pharmacology and safety data support the clinical development of AZD1163 as a novel therapeutic strategy for RA by reducing autoantigen load.
Resource
2026 EN
Zhou Ye · Yang Bo · Zhao Jianxin
+3 more
The infant gut microbiota, orchestrated by human milk oligosaccharides (HMOs), forms a critical foundation for lifelong health. Despite their recognized importance, the molecular strategies through which HMOs govern microbial competition and niche establishment remain poorly understood. Moving beyond ecological observations, this review synthesizes current mechanistic evidence on the molecular machinery of HMO metabolism in microbial assembly. We explore the specialized enzymes that confer competitive advantages and the metabolic networks fueled by HMO breakdown. Furthermore, we distinguish substrate-driven effects from the hypothesized signaling roles of intact HMOs in modulating host-microbe interactions, indicating where the evidence is associative versus causal. By integrating these pathways, we provide a blueprint for leveraging HMO biology to develop targeted nutritional interventions for preventing early-life disorders.
Journals
2026 EN
McCormick Beth M. · Wallander Sara E. · Miller Mark W.
+4 more
Background: Tinnitus is common among Veterans and is associated with PTSD and traumatic brain injury (TBI). Objective: To characterize tinnitus and examine the overlap of tinnitus, PTSD, and TBI and their relative associations with sleep disturbance, chronic pain, and cognitive and functional impairment. Method: Participants were 735 primarily young ( M = 34.7, SD = 9.1), male (90.2%) post-9/11 US Veterans. Hierarchical regressions were performed to determine whether additional variance in cross-sectional and longitudinal health outcomes was explained by tinnitus beyond PTSD and TBI. Results: Tinnitus was common (67.5%) and evidenced substantial comorbidity with both PTSD and TBI in 35.6% of the sample. Tinnitus explained an additional 1.9-3% of the variance (both Δ p < .001) in pain (β = .184, p < .001) and functional impairment (β = .145, p < .001) after accounting for PTSD severity and number of TBIs and adjusting for multiple testing. PTSD significantly predicted all outcomes (βs = −.226 -.657, all p s < .001). Tinnitus showed stability over time but did not predict later pain or functional impairment. Conclusions: Results suggest tinnitus is common among young treatment-seeking Veterans and highlight the need for future research aimed at reducing the toll of this chronic condition. Tinnitus should be evaluated alongside PTSD and TBI, as it may be associated with more negative health outcomes, even among those already at increased risk due to PTSD and TBI. Clinicians should be informed about best practices for managing tinnitus in efforts to improve health and well-being.
Journals
2026 EN
Tully Michael · Fennelly Aoife · Jackman Catherine
+4 more
Research documenting the self-reported impact of COVID-19 on people with intellectual disabilities has typically focused on the experiences of people with mild intellectual disabilities living in community settings. This study aimed to explore a broader perspective by examining the lived experiences of Irish adults with mild and moderate intellectual disabilities living in both community and congregated settings during COVID-19. Twenty-six adults with intellectual disabilities, of whom 20 lived in community settings, were interviewed in-person using easy read materials. Interviews were thematically analysed using Template Analysis. Five key themes were generated: (1) participants’ emotional response and the impact on relationships and mental and physical health; (2) reduced community access, changed services, and uncertainty; (3) loss of autonomy, greater restrictions, and unequal treatment; (4) self-reflection and reappraising the future through the lens of COVID-19; and (5) pandemic-generated opportunities, skills development, and resources for coping. Despite reference to some opportunities for growth and positive changes in routine, participants predominantly highlighted the negative impact of the pandemic on their emotional lives, relationships and sense of assurance of future stability in necessary supports. Participants’ experiences illustrate how the pandemic exposed the fragility of hard-fought advances in autonomy and self-determination. Greater vigilance is needed to protect a rights-based approach to support during times of emergency.
Journals
2026 EN
Coolen Catherine
This article considers the minimalist practice of artists Aaron Curme and Sungi Mlengeya to examine how similar economies of means create opposed spatial ethics. Through close looking, the analysis shows Curme bending reduction toward obstruction, treating whiteness as barricade and partition, while Mlengeya mobilises it for liberation, blank ground as breathable commons for Black women’s presence. Rather than a static interpretation, this study argues that African minimalism is a spectrum of situated tactics where absence acts as agentive expression. The article contributes language for labels and display, clarifies how reception shapes perception of ‘emptiness,’ and offers a transferrable framework for pairing abstraction with figuration in Africa-based case studies.
Journals
2026 EN
Cabrera Díaz Catherine Eliana · Cala Mónica P. · Jiménez-Díaz Elizabeth
+1 more
Malassezia globosa plays a crucial role as part of the human skin’s mycobiome. However, this yeast has been detected in other niches, such as the gut. Despite being commensal, the pathogenic link in several dermatological conditions, but recently, chronic diseases such as cancer, Crohn’s disease, and Parkinson’s disease, among others, have been explored. Lipids can be involved in fungal pathogenesis, and this yeast is characterized by a significant lipid metabolic versatility, with a lack of the complex fatty acid synthase (FAS) required for the de novo synthesis of fatty acids, as it relies on lipase-releasing enzymes. Here, we assess lipid dynamics (lipids consumed vs. lipids secreted) using lipidomic analysis in the supernatant of mDixon media during two growth phases. 87 lipids within 17 classes of lipids were identified in three different lipid uptake-secretion patterns. Some lipids were characteristic, including the presence of glycochenodeoxycholic acid, glycerophospholipids (such as phosphocholine), cardiolipins, and sphingolipids (such as Cer-PI). Interestingly, sterols, bile acids, cholic acid and its derivates, some phosphocholines, fatty acyls, and cardiolipins were lipids consumed over time. The dynamic consumption of these lipids could presume an intriguing role in the metabolism of lipid processes in this yeast that could determine the interaction process and its pathogenic role.
Journals
2026 EN
Gajevic Sayegh Alexandre · Cadieux Hubert · Ouellet Catherine
+2 more
This paper takes place at the intersection of climate policy, public opinion and the ‘just transition’ debate. Its central hypothesis is: the inclusion of fairness measures in the green economy transition – especially by targeting workers in the most affected sectors – will have a positive impact on the social acceptability of climate policy. This paper focuses on two key policies: carbon pricing and a fossil fuel phase-out. A set of survey questions compare social support for these two policies (i) without and (ii) with accompanying fairness provisions, such as green jobs creation and support for workers. This paper uses an exclusive survey ( n = 1,500) conducted in Canada in 2022. From the data, we observed that fairness provisions increase the support both for a higher price on carbon and for a decrease in the production of oil and gas, which was especially salient for groups initially less concerned by climate change.
Journals
2026 EN
Charrett Catherine
This paper reflects on what it means to be interpellated as threat through the European response to Hamas’s success in the 2006 Palestinian elections. While you might recognise elements of securitisation in this paper, here the performative utterance of threat relies on material and discursive histories of racism, sexism and colonialism to be successful. Securitisation is successful because it reiterates symbolic and material histories of permissible violence against racialised and sexualised subjects, normalised because the ‘securitised’ other have always been cast as threatening. This paper emphasises the asymmetries of power that mark the encounter between the European colonialist and Hamas, and the consequences of being marked as threatening entail. The securitisation of Hamas delivered through boycott, sanction and siege meant the collective punishment and death of the Palestinians and a coordinated imperial effort to dismantle local resistance. This paper interweaves excerpts from different performative texts: my interviews with European Union and Hamas representatives; theories of performativity and the questions of race and sex that shape contemporary developments this theory namely the works of Judith Butler and Sara Ahmed, and finally anti-colonial and anti-racist literatures, notably Toni Morrison and Frantz Fanon that describe experiences of being marked as less than human.
Journals
2026 EN
Kim Sanghee · Jai Tunmin (Catherine) · Chang Hyo Jung (Julie)
Many luxury brands have adopted artificial intelligence (AI) chatbots to offer personalized online shopping services. Underpinned by cognitive appraisal theory, this study examines sequential psychological mechanisms in AI chatbot-driven online luxury shopping experiences in information-seeking and problem-solving contexts. A between-subjects design (AI chatbot usage purposes: information-seeking vs. problem-solving) was employed, and 416 responses were collected in the United States. PLS-SEM was used for data analysis. The results reveal that AI chatbot service authenticity and perceived parasocial interaction increase pleasure and satisfaction, prompting online luxury purchase intention and brand loyalty. However, AI chatbot usage purposes did not serve as a moderator. This study contributes to AI chatbot service literature by adopting a consumer-centric approach to understanding the impact of AI-powered service agents on consumer engagement and commitment to luxury e-retailers. Furthermore, this research suggests that luxury brands develop an advanced level of personalization through AI chatbot services as an online retailing strategy to target Millennial and Generation Z consumers who desire a personalized touch. This study helps luxury brands enhance the effectiveness of chatbot services and achieve long-term profitability by leveraging AI-powered chatbots aligned with the brand’s identity and image.