Fetal Placental Thrombosis and Neonatal Implications

We present the neonatal complications of two premature newborn infants whose placentas demonstrated placental thrombosis in the fetal circulation. Both mothers presented with a 3-day history of decreased fetal movements before delivery. The first infant presented with thrombocytopenia and disseminated intravascular coagulation. The second infant had extended bilateral extended hemorrhagic venous infarctions. Severe fetal placental vascular lesions seem to be a predisposing factor for some adverse neonatal outcomes. We present these two cases with a brief review of the literature.

The role of heart-type fatty acid-binding protein in the diagnosis of acute coronary syndrome

Heart-type fatty acid-binding protein (H-FABP) is a membrane-bound protein that facilitates transport of fatty acids from the blood into the heart. It is currently being used outside the United States for the early diagnosis of myocardial infarction (MI). However, previous studies have shown inconsistent correlation of H-FABP with standard cardiac biomarkers.

Prevention of contrast-induced nephropathy: A randomized controlled trial of sodium bicarbonate and N-acetylcysteine

Contrast-induced nephropathy (CIN) continues to be a common cause of acute renal failure in high-risk patients undergoing radiocontrast studies. However, there is still a lack of consensus regarding the most effective measures to prevent CIN.

In Memoriam Steven A. Huesing (1944 - 2009)

On Sunday, April 12, 2009, Steven A. Huesing passed away. Since 1997 Steven Huesing was Executive Director of IMIA the International Medical Informatics Association [1]. In this prominent role he provided for many years signif icant and global contributions to the progress of our f ield. It was through his tireless work that IMIA has developed into the leading international association that it is today. When coming in touch with IMIA, many colleagues f irst communicated with him. And often he remained the major link to our association. As indicated by the messages, IMIA received after his death, colleagues of all parts of our world deeply miss him [2]. The sentence “IMIA presidents and other off icers were coming and going, and Steven was always there“, taken from this book of condolence, describes so well how many of us valued and respected him. Steven Huesing was born on September 8, 1944 in Bensheim, Germany. He moved to Canada with his mother and step-father, when he was 8 years old. At the beginning of Steven Huesing’s career in the 1960s, computers were still considered avant-garde and risky, even in a mainstream industry. Steven Huesing was a registered industrial and cost accountant. In 1967 he earned his CMA designation in at the University of Alberta. His interests in health informatics flourished, while he f illed senior administrative CFO and CIO roles with hospitals and government. His many accomplishments included [3]: • Serving Canada’s Health Informatics Association (COACH) in many capacities, including as Founding President (1975-78); Executive Director (1980-99), and editor of the COACH history book, covering 1975-2005. • Being the only Canadian to serve as President of IBM’s user group, Electronic Computing Health Oriented (ECHO) from 1983 to 1987. • Starting Healthcare Information Management & Communications Canada (HCIM&C), the only health informatics magazine in Canada for Fig. 1 Steven Huesing (1944 2009)

A Classic Twin Study of External Ear Malformations, Including Microtia

Rapid-Test Sensitivity for Novel Swine-Origin Influenza A (H1N1) Virus in Humans

Male Circumcision for the Prevention of HSV-2 and HPV Infections and Syphilis

Male circumcision significantly reduced the incidence of human immunodeficiency virus (HIV) infection among men in three clinical trials. We assessed the efficacy of male circumcision for the prevention of herpes simplex virus type 2 (HSV-2) and human papillomavirus (HPV) infections and syphilis in HIV-negative adolescent boys and men.

Comparison of Weight-Loss Diets with Different Compositions of Fat, Protein, and Carbohydrates

The possible advantage for weight loss of a diet that emphasizes protein, fat, or carbohydrates has not been established, and there are few studies that extend beyond 1 year.

Effect of Early versus Deferred Antiretroviral Therapy for HIV on Survival

The optimal time for the initiation of antiretroviral therapy for asymptomatic patients with human immunodeficiency virus (HIV) infection is uncertain.

Radiofrequency Ablation in Barrett's Esophagus with Dysplasia

Barrett's esophagus, a condition of intestinal metaplasia of the esophagus, is associated with an increased risk of esophageal adenocarcinoma. We assessed whether endoscopic radiofrequency ablation could eradicate dysplastic Barrett's esophagus and decrease the rate of neoplastic progression.