Journals
2018 EN
Liqian Dou · Jingqi Gao · Qun Zong
+1 more
In this paper, a multi-model switching control is developed for air-breathing hypersonic vehicle with variable geometry inlet(AHV-VGI). A variable geometry inlet with the translating cowl is adopted to capture the enough air mass flow for the scramjet engine, which can ensure a more powerful thrust. However, the using of VGI causes the unknown changes of the aerodynamics and thrust, making the model of AHV more complex. Therefore, we firstly analyze the thrust characteristic with the translating cowl and present the conception of optimal elongation distance of translating cowl(EDTC). Consequently, multiple different nonlinear aerodynamic models are constructed by curve fitting for each position of the translating cowl. Then, a switching mechanism dependent on EDTC is proposed and the adaptive RBF neural controllers are designed for velocity subsystem and altitude system of every model. Furthermore, the common Lyapunov functional is constructed to prove the stability of the multi-model switching process. Finally, numerical simulations are given to demonstrate the effectiveness of the proposed control approach for AHV-VGI.
Journals
2018 EN
Jingru Sun · Shengguo Yi · Lei Qiu
+10 more
Cutaneous CD30 + lymphoproliferative disorders (LPDs), including lymphomatoid papulosis (LyP) and primary cutaneous anaplastic large-cell lymphoma, comprise the second most common group of cutaneous T-cell lymphomas. Previously, we reported that special SATB1, a thymocyte-specific chromatin organizer, was overexpressed and promoted malignant T-cell proliferation in a portion of CD30 + LPDs. Here, we investigated the expression pattern of SATB1 in CD30 + LPDs with a large cohort of patient samples, and examined the potential of SATB1 as a molecular marker to classify CD30 + LPDs with differential clinicopathological behaviors. SATB1 expression was identified in the CD30 + anaplastic T cells in 11 of 12 (91.7%) lymphomatoid papulosis and 16 of 42 (38.1%) primary cutaneous anaplastic large-cell lymphoma cases. SATB1 + cases showed T-helper 17 polarization, together with more prominent epidermal hyperplasia and granulocytic infiltration. SATB1 + lesions responded better to combined treatment of methotrexate and interferon. SATB1 activated the expression of T-helper 17 cytokines while repressing T-helper 1-related genes. The heterogeneity in SATB1 expression across CD30 + LPDs was associated with the extent of promoter DNA methylation. Hence, SATB1 expression defines a subtype of CD30 + LPDs with characteristic pathobiology and prognosis. These data provide valuable insights into the heterogeneity of cutaneous T-cell malignancies, which may lead to individualized therapy in the future.
Journals
2018 EN
Dongyao Wu · Jinze Li · Jingru Guan
+7 more
Journals
2018 EN
En-Cai Xiao · Jianzhu Li · Jing Wang
+7 more
Journals
2018 EN
Hui Bian · Dongliang Bai · Zhiwen Jin
+6 more
Journals
2018 EN
Karsten Bruening · Benjia Dou · John Simonaitis
+3 more
Journals
2018 EN
Ranjusha Rajagopalan · Zhenguo Wu · Yumei Liu
+8 more
Current trends in battery research are promoting the development of feasible methods to prepare electrode materials with new architectures that can meet the requirements of high energy density associated with sodium ion batteries (SIB). It is logical to use solid-state processing techniques to fabricate SIB electrode materials due to its ease of handling and capability for large-scale production. From the SIB standpoint, the sulfate based polyanionic system is well known for its high operating voltage. The present study utilizes a hitherto-unknown solid-state process with an entirely new composition to develop an electrode comprising earth abundant carbon, sodium, sulfur, fluorine, and iron materials. This new NaFeSO4F-CNT system, where CNT is carbon nanotube, obtained by the solid-state technique, exhibits a highly stable Fe2+/Fe3+ redox couple and achieves a capacity of ∼110 mAg−1 at 0.1C with capacity retention of >91% after 200 cycles (1C). This is the best-ever reversible, high potential sulfate based cathode for sodium ion batteries reported to date. This study also provides an in-depth understanding of the outstanding electrochemical performance of this novel electrode. These findings can make it possible to achieve maximum performance from potential electrodes, when the operating temperature is limited to 350 °C or below.
Journals
2018 EN
Yanli Zhang · Tianhong Wang · Junqiang Lei
+5 more
Journals
2018 EN
Yafang Dou · Zonghui Liang
Journals
2018 EN
Genia Dubrovsky · YiKai Lo · PoMin Wang
+4 more
Pediatric gastrointestinal motility disorders are a large and broad group. Some of these disorders have been effectively treated with electrical stimulation. The goal of our present study is to determine whether the rate of intestinal peristalsis can be increased with electrical stimulation.