Virtual Learning Environments have been used constantly to help learning in classroom courses. UNIJUÍ University uses Conecta environment to do this task. It was developed at the university itself as aid tool to teachers and students. According to a survey on a group of students, the interaction between them and the Conecta is lower on mobile devices and supporting materials are not submitted in accordance with its dominance in the themes of the disciplines. Thus, this paper proposes the definition of an ontology, which connected to the integrated system, can be able to recommend support materials to students from disciplines of database according to context information. With the representation of ontology and inferences, it was possible to carry out the recommendation of support materials based on device capabilities and experience of students in the disciplines
In March 2012, the authors met at the National Evolutionary Synthesis Center (NESCent) in Durham, North Carolina, USA, to discuss approaches and cooperative ventures in Indo-Pacific phylogeography. The group emerged with a series of findings: (1) Marine population structure is complex, but single locus mtDNA studies continue to provide powerful first assessment of phylogeographic patterns. (2) These patterns gain greater significance/power when resolved in a diversity of taxa. New analytical tools are emerging to address these analyses with multi-taxon approaches. (3) Genome-wide analyses are warranted if selection is indicated by surveys of standard markers. Such indicators can include discordance between genetic loci, or between genetic loci and morphology. Phylogeographic information provides a valuable context for studies of selection and adaptation. (4) Phylogeographic inferences are greatly enhanced by an understanding of the biology and ecology of study organisms. (5) Thorough, range-wide sampling of taxa is the foundation for robust phylogeographic inference. (6) Congruent geographic and taxonomic sampling by the Indo-Pacific community of scientists would facilitate better comparative analyses. The group concluded that at this stage of technology and software development, judicious rather than wholesale application of genomics appears to be the most robust course for marine phylogeographic studies. Therefore, our group intends to affirm the value of traditional (''unplugged'') approaches, such as those based on mtDNA sequencing and microsatellites, along with essential field studies, in an era with increasing emphasis on genomic approaches
Working in the Galapagos Islands and surrounding areas, we examined the relationship between population structure, a precursor to allopatric speciation, in species of reef fishes that exhibit different life history traits and three types of distributions in a nested setting: endemic (restricted to the Galapagos Islands), insular (Galapagos and neighboring islands), and Panamic (tropical eastern Pacific). We used a combination of population structure and coalescent approaches to assess the degree of genetic population structure in the three groups of fish species. In addition, we evaluated the level of inter-island genetic diversity in endemic species to determine if Galapagos fishes, like their terrestrial counterparts, could be used as a system to study allopatric speciation in the sea. We found that in general, there was no correlation between distribution ranges, life history traits, and population structure, except for Dialommus fuscus Gilbert, 1891, a Galapagos endemic that lives in the uppermost intertidal area, and as predicted, shows very strong population structure. We found the highest number of statistically significant population pairwise F ST comparisons in endemic species. In addition, three out of four endemic species showed significant population pairwise F ST [D. fuscus, Lepidonectes corallicola (Kendall and Radcliffe, 1912), and Lythrypnus gilbert (Heller and Snodgrass, 1903)]. These results suggest that endemic Galapagos Islands reef fishes may be a promising group of species to study phylogeographic patterns of speciation.
O desenvolvimento das técnicas e os avanços no campo científico possibilitaram a ampliação da capacidade interventora das sociedades sobre os ambientes, modificando-os de acordo com as demandas por recursos necessários à sua sobrevivência. Tal capacidade está relacionada às características sociais, políticas, econômicas e culturais dos diferentes grupos humanos. Dada a magnitude das intervenções antrópicas nas paisagens, observam-se inúmeras alterações nas dinâmicas e processos naturais, especialmente aqueles relacionados ao relevo e aos solos. A materialização destas modificações pode ocorrer, entre outras formas, através da gênese de depósitos tecnogênicos, constituídos por materiais sedimentares acrescidos de artefatos diversos, produto das diferentes atividades humanas desenvolvidas ao longo do processo histórico. Em áreas urbanas, estes depósitos têm sua gênese relacionada ao uso-ocupação do solo, considerando-se as práticas realizadas no intuito de adequar as características do meio físico às necessidades dos citadinos. Estas práticas resultam, por vezes, na instalação de um quadro de degradação ambiental, caracterizado pela ocorrência de erosão antrópica, assoreamento, disposição inadequada de resíduos sólidos, entre outros. Sob essa perspectiva, este trabalho objetiva retratar a ação antrópica e seus desdobramentos sobre o ambiente urbano, materializados por meio da formação dos depósitos e coberturas tecnogênicas. Para tanto, elegeram-se três áreas de estudo localizadas nos municípios de Goiânia (GO), São Pedro (SP) e Presidente Prudente (SP), visto que estas localidades apresentam similitudes quanto à formação de depósitos e coberturas tecnogênicas relacionados ao uso-ocupação do solo, possibilitando uma análise comparativa entre os diferentes contextos socioambientais.
This paper’s main purpose is to propose and discuss a specific geological classification (termed geotechnogenic) of artificial ground, that is, the new ground types formed as a direct or indirect result of human action, be it related to erosion or deposition processes or whilst in situ modification of the natural land. These technogenic grounds are classified into four main categories, namely the aggraded ground , the degraded ground , the modified and the mixed ground, each of them is subdivided into specific genetic types. The foundations of the proposal are derived from two main “schools” of thinking about the geological products of mankind’s activity, on one hand the British works on the artificial ground and, on the other hand, the former Soviet, after Russian and east European studies on technogenic deposits and soils. These contributions have been compared with and joined to the American and Brazilian contributions on the study of technogenic deposits, leading to a comprehensive and synthetic table that can be used for basic purposes of geological and geotechnical analysis and mapping of land areas transformed by human action, as well as to aid their geomorphologic interpretation and mapping. .
The shaping of the Earth’s surface by human geological action has produced original landform types, namely technogenic landforms. In this paper we will revise the conceptual framework concerning the geomorphic agency of humankind and introduce a new proposal for classifying these new landforms, which join the existing criteria for the identification of technogenic processes, the analysis of technogenic layers and the characterisation of the resulting newly formed technogenic ground. The proposal itself is enhanced by a taxonomic classification which considers the technogenic landforms as constituent parts of the land shape compartments that, by their way, form extensive technogenic landscapes. The classification was applied to the geomorphologic mapping of two urban areas in Presidente Prudente City (Sao Paulo State, Brazil) in which technogenic ground occurs.
The treatment of choice for thrombotic thrombocytopenic purpura, a disorder in platelet aggregation with inordinate hemolysis and microvascular occlusion, consists of plasmapheresis and corticosteroids. However, there are cases refractory to this therapy and Rituximab, a monoclonal anti-CD20 antibody appears to be an alternative. We report a case of a 35-year-old woman with signs of bleeding and neurological impairment, who underwent plasmapheresis, and after developed hemodynamic instability. After trying plasmapheresis without success, Rituximab was administered 375mg / m², associated with plasmapheresis. She evolved with clinical and laboratory improvement. Rituximab appears to be an option in cases of refractory TTP, but randomized controlled trials are still needed to better establish its role.
A Síndrome Hipereosinofílica é uma desordem rara com prevalência estimada entre 0.36-6.3/100.000 habitantes, com seu diagnóstico através da contagem absoluta de eosinófilos superior a 1500 células/mm³ em duas medidas com intervalo mínimo entre elas de quatro semanas e/ou aumento no número de eosinófilos nos tecidos. Além disso, é preciso que haja lesão/disfunção orgânica associada e exclusão de causas potenciais de eosinofilia.Este é um caso de um paciente masculino, 49 anos, com um quadro de dispneia aos pequenos esforços, edema e dor em panturrilha direita, sem outras comorbidades prévias. Ao hemograma verificou-se a média de 30.021 eosinófilos, ultrassonografia de membros inferiores com trombose venosa em veia femoral direita, e tomografia torácica demonstrando trombo distal em artéria pulmonar direita. Apesar de essa síndrome ser rara, sempre deve-se estar atento para suspeitar do seu diagnóstico e trata-la rapidamente, evitando complicações letais.