Over the years, nanotechnology has gained a rapidly growing in various aspects such as agricultural, environmental and health management. Since, little information is available relating using nanoparticles as antimicrobial agent. Thus, this work was initiated to assess the antifungal activity of curcumin-Silver nanoparticles (Cr-AgNPs) against pathogenic Saprolegnia spp. in common carp. Around of 120 Cyprinus carpio(20 fish treatment) were infected with Saprolegnia (2x10 zoospore l) and treated with different series (4, 8 and 12 mg l) of Cr-AgNPs (size 30 nm) and a treatment as reference (“formalin; 0.15 ml l, 30 min”) and two treatments one acted as positive control “infected with Saprolegnia spp. without disinfectants” and one was served negative control without any disinfectants. After 14 days of treatment, results of blood sets, RBCs, WBCs count and hemoglobin content were recorded significantly (P<0.05) increased in T3 (12mg l of Cr-AgNPs) relative to C+ group. Considerable changes in TP, albumin and globulin were observed in all Cr-AgNPs and formalin group in comparison to positive groups (C+). Albumin illustrated a significant decrease (p<0.01)in all Cr-AgNPs and formalin treatments relative to C+group.As a result, all the Cr-AgNPs treated groups showed highest survival rate than C+ group, the maximal survival was noticed in T3 (85%) indicating the antifungal efficacy of Cr-AgNPs against pathogenic Saprolegnia. This offers new evidence about the effectiveness of nanoparticles on aquatic species. Further studies are required of the antifungal and antibacterial activities of Cr-AgNPs against other pathogens in fish.
Complexes of transition metals with chiral ligands are considered as catalysts. Among metal-containing organic complexes with semiconducting properties, compounds of the porphin series occupy a special place in electrocatalytic studies. The properties of the porphyrin macrocycle, their role in catalysis, and the influence of the nature of the metal on the catalytic properties of the complex are considered.